1400681-59-5

Basic information

• Product Name: 3-((4-nitrobenzyloxy)carbonyl)-9,10-dioxo-9,10-dihydroanthracene-1,8-diyl diacetate
• Synonyms: 3-((4-nitrobenzyloxy)carbonyl)-9,10-dioxo-9,10-dihydroanthracene-1,8-diyl diacetate
• CAS NO: 1400681-59-5
• Molecular Weight: 503.422
• Mol File: 1400681-59-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-((4-nitrobenzyloxy)carbonyl)-9,10-dioxo-9,10-dihydroanthracene-1,8-diyl diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-((4-nitrobenzyloxy)carbonyl)-9,10-dioxo-9,10-dihydroanthracene-1,8-diyl diacetate(1400681-59-5)
• EPA Substance Registry System: 3-((4-nitrobenzyloxy)carbonyl)-9,10-dioxo-9,10-dihydroanthracene-1,8-diyl diacetate(1400681-59-5)

Safety Data

• Hazardous Substances Data: 1400681-59-5(Hazardous Substances Data)

Upstream product

• 478-43-3 1,8-dihydroxy-3-carboxy-anthraquinone 
• 619-73-8 4-nitrobenzyl chloride 
• 13739-02-1 diacetylrhein 

Relevant articles and documents

Synthesis and hypoglycemic activity evaluation of rhein amide derivatives

In order to investigate the relationship of the structure and hypoglycemic activity, rhein amide derivatives 2a-2e were synthesized and their hypoglycemic activities were evaluated by glucose consumption in HepG2. Their structures were characterized by 1H-, 13C NMR, IR, mass and elemental analysis. All the compounds exhibited strong hypoglycemic activity in improving glucose consumption in HepG2 cell assays in vitro, which was influenced by the diversity of rhein amide derivatives. The compounds 2a-c, 2f, and 2g bearing heterocyclic ring were proved to be more potentially useful in glucose consumption than dimethyldiguanide. Among all the compounds, compound 2f exhibited the strongest activity on glucose consumption, while compound 2d showed the weakest activity.