1400693-93-7Relevant articles and documents
Chiral Bronsted acid-catalyzed diastereo- and enantioselective synthesis of CF3-substituted aziridines
Chai, Zhuo,Bouillon, Jean-Philippe,Cahard, Dominique
supporting information, p. 9471 - 9473 (2012/10/30)
A multicomponent organocatalyzed highly diastereo- and enantioselective synthesis of CF3-substituted aziridines is described. This reaction of in situ generated CF3CHN2 and aldimines was realized by chiral Bronsted acid catalysis. The utility of the products is illustrated by easy access to β-CF3 isocysteine and aziridine-containing dipeptides.