1400706-57-1

Basic information

• Product Name: (N-cyclopropyl)-4-oxazol-5-yl-(N-piperidin-4-yl)benzamide
• Synonyms: (N-cyclopropyl)-4-oxazol-5-yl-(N-piperidin-4-yl)benzamide
• CAS NO: 1400706-57-1
• Molecular Weight: 311.384
• Mol File: 1400706-57-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (N-cyclopropyl)-4-oxazol-5-yl-(N-piperidin-4-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: (N-cyclopropyl)-4-oxazol-5-yl-(N-piperidin-4-yl)benzamide(1400706-57-1)
• EPA Substance Registry System: (N-cyclopropyl)-4-oxazol-5-yl-(N-piperidin-4-yl)benzamide(1400706-57-1)

Safety Data

• Hazardous Substances Data: 1400706-57-1(Hazardous Substances Data)

Upstream product

• 250161-45-6 4-(1,3-oxazol-5-yl)benzoic acid 
• 179557-01-8 4-cyclopropylamino-piperidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 1400706-58-2 N-(1-cyanopiperidin-4-yl)-N-cyclopropyl-4-oxazol-5-ylbenzamide 
• 1400707-76-7 N-cyclopropyl-N-[1-(5-methylpyrazin-2-yl)piperidin-4-yl]-4-oxazol-5-ylbenzamide 
• 1400708-04-4 N-cyclopropyl-N-[1-(5-cyclopropylpyrimidin-2-yl)piperidin-4-yl]-4-oxazol-5-ylbenzamide 
• 1400707-15-4 N-cyclopropyl-N-[1-(3-isopropyl-[1,2,4]oxadiazol-5-yl)piperidin-4-yl]-4-oxazol-5-ylbenzamide 
• 1400707-62-1 N-cyclopropyl-4-oxazol-5-yl-N-[1-(5-phenyl-[1,2,4]oxadiazol-3-yl)piperidin-4-yl]benzamide 
• 1400706-74-2 N-cyclopropyl N-[1-(N-hydroxycarbamimidoyl)piperidin-4-yl]-4-oxazol-5-ylbenzamide 
• 1578187-99-1 4-[cyclopropyl-(4-oxazol-5-yl-benzoyl)-amino]-piperidine-1-carboxylic acid tetrahydro-pyran-4-yl ester 
• 1578190-69-8 4-[cyclopropyl-(4-oxazol-5-yl-benzoyl)-amino]-piperidine-1-carboxylic acid 4-nitro-phenyl ester 
• 1578190-31-4 4-[cyclopropyl-(4-oxazol-5-yl-benzoyl)-amino]-piperidine-1-carboxylic acid methyl ester 
• 1578187-76-4 4-[cyclopropyl-(4-oxazol-5-yl-benzoyl)-amino]-piperidine-1-carboxylic acid isopropenyl ester 
• 1578190-58-5 4-[cyclopropyl-(4-oxazol-5-yl-benzoyl)-amino]-piperidine-1-carboxylic acid 2,2,2-trifluoro-1,1-dimethyl-ethyl ester 
• 1400707-88-1 N-cyclopropyl-N-[1-(6-cyclopropylpyridazin-3-yl)piperidin-4-yl]-4-oxazol-5-ylbenzamide 
• 1400707-89-2 N-cyclopropyl-N-(3'-fluoro-5'-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-4-oxazol-5-ylbenzamide 
• 1400707-87-0 N-(5'-bromo-3'-fluoro-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-N-cyclopropyl-4-oxazol-5-ylbenzamide 

Relevant articles and documents

N-CYCLOPROPYL-N-PIPERIDINYL-AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USES THEREOF

The present invention relates to compounds of general formula I, wherein R1, LP, (Het)Ar1, (Het)Ar2 and n are as defined in the application, which have valuable pharmacological properties, and in particular bind

N-CYCLOPROPYL-N-PIPERIDINYL-AMIDE DERIVATIVES AND THEIR USE AS GPR119 MODULATORS

The present invention relates to compounds of general formula I wherein R1 is selected from a group consisting of -CH2-Ra, wherein Ra denotes C1-6-alkyl optionally mono- or polysubstituted with fluorine, or C3-6- cycloalkyl optionally mono- or polysubstituted with fluorine and optionally substituted with a group selected from among CH3, CF3, and CHF2, and Lp, (Het)Ar1, (Het)Ar2 and n are as defined in the application, which have valuable pharmacological properties, and in particular bind to the GPR119 receptor and modulate its activity.

N- CYCLOPROPYL - N- PIPERIDINYLBENZAMIDES AS GPR119 MODULATORS

The present invention relates to compounds of general formula I, wherein the groups R1, LP, LQ, Ar, mand n are as defined in the application, which have valuable pharmacological properties, and in particular bind to the GPR119 receptor and modulate its activity.