1401052-74-1

Basic information

• Product Name: 4-hydroxy-1,2-diphenylphenanthrene-3-carbonitrile
• CAS NO: 1401052-74-1
• Molecular Weight: 371.438
• Mol File: 1401052-74-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-hydroxy-1,2-diphenylphenanthrene-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydroxy-1,2-diphenylphenanthrene-3-carbonitrile(1401052-74-1)
• EPA Substance Registry System: 4-hydroxy-1,2-diphenylphenanthrene-3-carbonitrile(1401052-74-1)

Safety Data

• Hazardous Substances Data: 1401052-74-1(Hazardous Substances Data)

Upstream product

• 39528-57-9 2-(naphthalen-1-carbonyl)acetonitrile 
• 501-65-5 diphenyl acetylene 

Relevant articles and documents

Rhodium-catalyzed cascade oxidative annulation leading to substituted naphtho[1,8- bc ]pyrans by sequential cleavage of C(sp2)-H/C(sp 3)-H and C(sp2)-H/O-H Bonds

The cascade oxidative annulation reactions of benzoylacetonitrile with internal alkynes proceed efficiently in the presence of a rhodium catalyst and a copper oxidant to give substituted naphtho[1,8-bc]pyrans by sequential cleavage of C(sp2)-H/C(sp3)-H and C(sp2)-H/O-H bonds. These cascade reactions are highly regioselective with unsymmetrical alkynes. Experiments reveal that the first-step reaction proceeds by sequential cleavage of C(sp2)-H/C(sp3)-H bonds and annulation with alkynes, leading to 1-naphthols as the intermediate products. Subsequently, 1-naphthols react with alkynes by cleavage of C(sp2)-H/O-H bonds, affording the 1:2 coupling products. Moreover, some of the naphtho[1,8-bc]pyran products exhibit intense fluorescence in the solid state.