140137-33-3

Basic information

• Product Name: 1H-Pyrrole, 1-(2,4-dimethylphenyl)-2,5-dimethyl-
• CAS NO: 140137-33-3
• Molecular Formula: C14H17N
• Molecular Weight: 199.296
• Mol File: 140137-33-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole, 1-(2,4-dimethylphenyl)-2,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole, 1-(2,4-dimethylphenyl)-2,5-dimethyl-(140137-33-3)
• EPA Substance Registry System: 1H-Pyrrole, 1-(2,4-dimethylphenyl)-2,5-dimethyl-(140137-33-3)

Safety Data

• Hazardous Substances Data: 140137-33-3(Hazardous Substances Data)

Upstream product

• 109-49-9 5-Hexen-2-one 
• 95-68-1 2,4-Xylidine 
• 110-13-4 2,5-hexanedione 

Downstream Products

• 328028-87-1 C₁₅H₁₇NO 
• 471885-11-7 C₂₀H₂₃N₃OS 

Relevant articles and documents

Microwave assisted synthesis of pyrroles

The synthesis of pyrroles by reaction of hexane-2,5-dione with primary amines has been shown to occur in less than 2 minutes under microwave activation.

Synthesis of Fe3O4@L-proline@SO3H as a novel and reusable acidic magnetic nanocatalyst and its application for the synthesis of N-substituted pyrroles at room temperature under ultrasonic irradiation and without solvent

N-Substituted pyrroles have been prepared in high isolated yields (65–90%) by the reaction of hexane-2,5-dione with amines or diamines in the presence of Fe3O4@L-proline@SO3H at ambient temperature under ultrasonic irradiation and without solvent. The experimental procedure involves simple operations, and the products are readily separated by external magnet. The same reaction of hexane-2,5-dione with amines containing electron-acceptor substituents, such as 4-nitroaniline, resulted in fair yields of pyrrole derivatives.

Efficient synthesis of substituted pyrroles through Pd(OCOCF3)2-catalyzed reaction of 5-hexen-2-one with primary amines

An efficient and facile Pd(OCOCF3)2-catalyzed one-pot cascade protocol has been developed for the synthesis of multiple substituted pyrroles in good to excellent yields. Unlike the reported method starting from the 2-alkenal-1,3-carbonyl compounds, the process utilizes the less reactive 5-hexen-2-one and the method has great potential as a complement to the current developed methods.