1401424-87-0Relevant articles and documents
Enantioselective iridium-catalyzed hydrogenation of 3,4-disubstituted isoquinolines
Shi, Lei,Ye, Zhi-Shi,Cao, Liang-Liang,Guo, Ran-Ning,Hu, Yue,Zhou, Yong-Gui
, p. 8286 - 8289 (2012)
Reining in the outliers: An efficient approach for enantioselective hydrogenation of 3,4-disubstituted isoquinolines was successfully developed. When isoquinolines are treated with [Ir(cod)Cl]2/(R)-synphos in the presence of 1-bromo-3-chloro-5,