1401518-57-7Relevant articles and documents
Rhodium(III)-catalyzed intermolecular cyclization of anilines with sulfoxonium ylides toward indoles
Shen, Zhihao,Pi, Chao,Cui, Xiuling,Wu, Yangjie
, p. 1374 - 1378 (2019)
Rhodium(III)-catalyzed synthesis of indole derivatives has been realized via cascade reaction of C–H alkylation/nucleophilic cyclization starting from readily available N-phenylpyridin-2-amines and sulfoxonium ylides. Notably, this transformation could smoothly proceed with high yields, good regioselectivity, and feature broad group tolerance and under redox-neutral condition to avoid external oxidant. The titled products are potentially important building blocks in the organic synthesis through various chemical transformations.
Synthesis of 2-substituted indoles by iridium (III)-catalyzed C–]H functionalization of N-phenylpyridin-2-amines
Zhang, Lei,Chen, Junyu,Chen, Jinkang,Jin, Licheng,Zheng, Xiangyun,Jiang, Xinpeng,Yu, Chuanming
, p. 1053 - 1056 (2019/03/20)
A highly regioselective synthesis of 2-substituted indoles was realized through Ir(III)-catalyzed C–]H functionalization of N-phenylpyridin-2-amines followed by the reaction with sulfoxonium ylides and intramolecular cyclization under mild conditions. The reaction completed with broad range of substrate scopes and gave various 2-substituted indoles in up to 98% yields.
Synthesis of 2-Arylindoles through Pd(II)-Catalyzed Cyclization of Anilines with Vinyl Azides
Jie, Lianghua,Wang, Lianhui,Xiong, Dan,Yang, Zi,Zhao, Di,Cui, Xiuling
, p. 10974 - 10984 (2018/09/06)
Vinly azides are featured as electrophiles, nucleophiles, and radical acceptors in synthetic chemistry and have emerged as rapid and versatile synthons in the preparation of N-heterocyclic systems. Herein, a novel approach to 2-arylindoles via Pd(II)-catalyzed cyclization reaction of anilines with vinyl azides has been achieved, which furnishes the versatile 2-arylindoles with high efficieny and excellent regioselectivity.
