1401870-95-8Relevant articles and documents
KI-catalyzed imidation of sp3 C-H bond adjacent to amide nitrogen atom
Lao, Zhi-Qi,Zhong, Wen-He,Lou, Qing-Hua,Li, Zhong-Jun,Meng, Xiang-Bao
, p. 7869 - 7871 (2012)
We have developed a new KI-catalyzed method for the imidation of an sp 3 C-H bond adjacent to an amide nitrogen atom by using TBHP (tert-butyl hydroperoxide, 70% aqueous solution) as the oxidant. This novel procedure tolerated air and moisture and provided a series of novel products in moderate to excellent yields under mild conditions.