140195-93-3Relevant articles and documents
UREA DERIVATIVES AS PYRUVATE KINASE ACTIVATORS
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Paragraph 539-541, (2022/02/15)
The subject matter described herein is directed to pyruvate kinase activating compounds of Formula I and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds and methods of administering the compounds for the treatment of diseases associated with PKR and/or PKM2, such as pyruvate kinase deficiency, sickle cell disease, and beta-thalassemia.
A fast procedure for the preparation of amides/peptides from carboxylic acids and azides via two redox reactions: Application to the synthesis of methionine enkephalin
Ghosh, Sunil K.,Verma, Rekha,Ghosh, Usha,Mamdapur, Vasant R.
, p. 1705 - 1711 (2007/10/03)
A one-pot self regulated approach for the synthesis of amides/peptides based on two reduction-oxidation (redox) reactions has been described. The primary and secondary amides/peptides are made by using azidotrimethylsilane and alkyl azides/α-azido acid de
Syntheses and antibacterial activity of novel 6-fluoro-7-(gem-disubstituted piperazin-1-yl)-quinolines
Chu,Claiborne,Clement,Plattner
, p. 1328 - 1337 (2007/10/02)
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