140223-15-0 Usage
Description
1,2,3,4-Tetra-O-benzoyl-L-fucopyranose, with the CAS number 140223-15-0, is a white solid compound that is primarily utilized in the field of organic synthesis. It is a derivative of L-fucopyranose, a sugar molecule, with four benzoyl groups attached to its hydroxyl groups. This modification enhances its reactivity and compatibility with various organic reactions, making it a valuable intermediate in the synthesis of complex organic molecules.
Uses
Used in Organic Synthesis:
1,2,3,4-Tetra-O-benzoyl-L-fucopyranose is used as a synthetic intermediate for the production of various complex organic molecules. Its application is primarily due to its unique structure, which allows for selective functionalization and the formation of diverse chemical entities. The benzoyl groups can be selectively removed or modified, enabling the synthesis of a wide range of target compounds.
Used in Pharmaceutical Industry:
1,2,3,4-Tetra-O-benzoyl-L-fucopyranose is used as a building block for the development of novel pharmaceutical compounds. Its unique structure and reactivity make it an attractive candidate for the design of new drugs with potential therapeutic applications. The compound can be further modified and functionalized to create molecules with specific biological activities, such as anti-cancer, anti-inflammatory, or anti-microbial properties.
Used in Chemical Research:
1,2,3,4-Tetra-O-benzoyl-L-fucopyranose is also used as a research tool in the field of chemistry. Its unique structure and reactivity make it an interesting subject for studying various organic reactions, reaction mechanisms, and the development of new synthetic methodologies. Additionally, it can be used to investigate the properties of sugar derivatives and their interactions with other molecules, providing valuable insights into the chemistry of carbohydrates and their potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 140223-15-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,0,2,2 and 3 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 140223-15:
(8*1)+(7*4)+(6*0)+(5*2)+(4*2)+(3*3)+(2*1)+(1*5)=70
70 % 10 = 0
So 140223-15-0 is a valid CAS Registry Number.
140223-15-0Relevant articles and documents
Boronic acid-catalyzed final-stage site-selective acylation for the total syntheses of O-3′-acyl bisabolol β-D-fucopyranoside natural products and their analogues
Nakamura, Yuki,Ochiai, Takayuki,Makino, Kazuishi,Shimada, Naoyuki
, p. 281 - 285 (2021/03/08)
The first concise total syntheses of O-3′-senecioyl α-bisabolol β-D-fucopyranoside (4a) and O-3′isovaleroyl α-bisabolol β-D-fucopyranoside (4b) were achieved through final-stage site-selective acylation via the activation of cis-vicinal diols by imidazole
Sterically Hindered 2,4,6-Tri- tert-butylpyridinium Salts as Single Hydrogen Bond Donors for Highly Stereoselective Glycosylation Reactions of Glycals
Ghosh, Titli,Mukherji, Ananya,Kancharla, Pavan K.
supporting information, p. 3490 - 3495 (2019/05/24)
We demonstrate here that the strained and bulky protonated 2,4,6-tri-tert-butylpyridine salts serve as efficient catalysts for highly stereoselective glycosylations of various glycals. Moreover, the mechanism of action involves an interesting single hydrogen bond mediated protonation of glycals and not via the generally conceived Br?nsted acid pathway. The counteranions also play a role in the outcome of the reaction.
BIARYL AMIDES WITH MODIFIED SUGAR GROUPS FOR TREATMENT OF DISEASES ASSOCIATED WITH HEAT SHOCK PROTEIN PATHWAY
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Page/Page column 146; 180; 186-187, (2019/12/04)
Provided are biaryl amides and coumarin-based compounds with modified sugar groups for treatment of diseases associated with heat shock protein pathway. The compounds having the following formulas, wherein variables are as defined herein. Formulae (I), (II), (III), (IV), and (V), Pharmaceutical compositions of the compounds are also provided. These biaryl amides and coumarin-based derivatives with modified sugar groups are useful for treatment and prevention of diseases and disorders, including neurological disorders, such as neurodegenerative diseases and nerve damaging disorders, for example, diabetic peripheral neuropathy.