140239-17-4

Basic information

• Product Name: 2-Cyclohexene-1-carboxylic acid, 1-methyl-4-oxo-2-(trifluoromethyl)-, ethyl ester
• CAS NO: 140239-17-4
• Molecular Formula: C11H13F3O3
• Molecular Weight: 250.218
• Mol File: 140239-17-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Cyclohexene-1-carboxylic acid, 1-methyl-4-oxo-2-(trifluoromethyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexene-1-carboxylic acid, 1-methyl-4-oxo-2-(trifluoromethyl)-, ethyl ester(140239-17-4)
• EPA Substance Registry System: 2-Cyclohexene-1-carboxylic acid, 1-methyl-4-oxo-2-(trifluoromethyl)-, ethyl ester(140239-17-4)

Safety Data

• Hazardous Substances Data: 140239-17-4(Hazardous Substances Data)

Upstream product

• 344-00-3 ethyl 2-methyl-4,4,4-trifluoroacetoacetate 

Relevant articles and documents

MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF

Non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-?B activity including obesity, diabetes, inflammatory and immune diseases, and have the structure of formula (I) or an enantiomer, a diastereomer, a pharmaceutically acceptable salt, or hydrate thereof, where J is selected from NR1 or C(R4)(R4a); K is selected from NR2 or C(R5)(R5a); L is selected from NR3 or C(R6)(R6a); and A, X, Y, R1, R2, R3, R4, R4a, R5, R5a, R6, R6a, R8, R10, R11, and n are defined herein. Also provided are pharmaceutical compositions and methods of treating obesity, diabetes and inflammatory or immune associated diseases comprising said compounds.