1403336-55-9Relevant articles and documents
Lewis acid-catalyzed Friedel-Crafts alkylations of 3-hydroxy-2-oxindole: An efficient approach to the core structure of azonazine
Ghosh, Santanu,Kinthada, Lakshmana K.,Bhunia, Subhajit,Bisai, Alakesh
, p. 10132 - 10134 (2012/11/13)
A Lewis acid catalyzed Friedel-Crafts reaction of electron rich aromatics with 3-alkyl-3-hydroxy-2-oxindole (5) has been developed. The methodology provides a straightforward access to the core of azonazine (2) sharing an all-carbon quaternary stereocenter at the tetracyclic ring junction. The Royal Society of Chemistry 2012.