1403385-04-5Relevant articles and documents
A synthetic receptor for nicotine from a dynamic combinatorial library
Hamieh, Saleh,Ludlow, R. Frederick,Perraud, Olivier,West, Kevin R.,Mattia, Elio,Otto, Sijbren
, p. 5404 - 5407 (2012)
Designing synthetic receptors that bind biologically relevant guests in an aqueous solution remains a considerable challenge. We now report a new synthetic receptor for nicotine, selected from a dynamic combinatorial library, that binds this guest in water at neutral pH through a combination of hydrophobic and π-π interactions.