1403611-75-5Relevant articles and documents
CuI controlled C-C and C-N bond formation of heteroaromatics through C(sp3)-H activation
Xia, Ran,Niu, Hong-Ying,Qu, Gui-Rong,Guo, Hai-Ming
supporting information, p. 5546 - 5549 (2013/01/15)
A new method for C-C and C-N bond formation of heteroaromatics and C(sp3)-H alkanes was developed with high regioselectivity. The reaction occurred on C8 to give 8-cylcoakylpurines by C-C bond formation only promoted by tBuOOtBu, while it occurred on the amino group to give N6-alkylated purines by C-N bond formation when 2 equiv of CuI were added. A reaction mechanism was also proposed based on our preliminary experimental data.