140372-83-4Relevant articles and documents
Iron-Catalyzed Azidoalkylthiation of Alkenes with Trimethylsilyl Azide and 1-(Alkylthio)pyrrolidine-2,5-diones
Yu, Jipan,Jiang, Min,Song, Zhixuan,He, Tiancheng,Yang, Haijun,Fu, Hua
, p. 2806 - 2810 (2016)
A simple, efficient and practical iron-catalyzed azidoarylthiation of alkenes has been developed at room temperature, and the corresponding products containing ortho-sited sulfide and azide units were obtained in moderate to good yields with good tolerance of functional groups. The protocol uses readily available 1-(alkylthio)pyrrolidine-2,5-diones and trimethylsilyl azide as the alkylthiation and azidation reagents, respectively, inexpensive and environmentally friendly iron chloride as the catalyst without addition of any ligand and additive. (Figure presented.).
Synthesis of mexiletine analogues from non-activated aziridines
Ingebrigtsen, Truls,Lejon, Tore
, p. 891 - 902 (2008/03/13)
A general method for the synthesis of mexiletine analogues by nucleophilic ring opening of non-activated racemic aziridines has been developed (Scheme 1). Structural variation is introduced by employing different nucleophiles or by altering the substitution on the aziridine ring.
An efficient procedure for cleavage of aziridines with various thiols promoted by ZnCl2
Wu,Hou,Dai
, p. 1314 - 1317 (2007/10/03)
The ring-opening reaction of aziridines with various thiophenols and thiols catalyzed by ZnCl2 provides β-amino sulfides in high yield.