1403879-40-2

Basic information

• Product Name: 5-fluoro-2-(1-phenylethyl)benzo[d][1,2]selenazol-3(2H)-one
• Synonyms: 5-fluoro-2-(1-phenylethyl)benzo[d][1,2]selenazol-3(2H)-one
• CAS NO: 1403879-40-2
• Molecular Weight: 320.225
• Mol File: 1403879-40-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-fluoro-2-(1-phenylethyl)benzo[d][1,2]selenazol-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-fluoro-2-(1-phenylethyl)benzo[d][1,2]selenazol-3(2H)-one(1403879-40-2)
• EPA Substance Registry System: 5-fluoro-2-(1-phenylethyl)benzo[d][1,2]selenazol-3(2H)-one(1403879-40-2)

Safety Data

• Hazardous Substances Data: 1403879-40-2(Hazardous Substances Data)

Upstream product

• 7782-49-2 selenium 
• 1403879-66-2 2-chloro-5-fluoro-N-(1-phenylethyl)benzamide 
• 21900-51-6 2-chloro-5-fluorobenzoyl chloride 
• 618-36-0 rac-methylbenzylamine 

Relevant articles and documents

Isoselenazolones as catalysts for the activation of bromine: Bromolactonization of alkenoic acids and oxidation of alcohols

Isoselenazolones were synthesized by a copper-catalyzed Se-N bond forming reaction between 2-halobenzamides and selenium powder. The catalytic activity of the various isoselenazolones was studied in the bromolactonization of pent-4-enoic acid. Isoselenazolone 9 was studied as a catalyst in several reactions: the bromolactonization of a series of alkenoic acids with bromine or N-bromosuccinimide (NBS) in the presence of potassium carbonate as base, the bromoesterification of a series of alkenes using NBS and a variety of carboxylic acids, and the oxidation of secondary alcohols to ketones using bromine as an oxidizing reagent. Mechanistic details of the isoselenazolone-catalyzed bromination reaction were revealed by 77Se NMR spectroscopic and ES-MS studies. The oxidative addition of bromine to the isoselenazolone gives the isoselenazolone(IV) dibromide, which could be responsible for the activation of bromine under the reaction conditions. Steric effects from an N-phenylethyl group on the amide of the isoselenazolone and electron-withdrawing fluoro substituents on the benzo fused-ring of the isoselenazolone appear to enhance the stability of the isoselenazolone as a catalyst for the bromination reaction.