1403991-96-7Relevant articles and documents
First total synthesis of salinipyrone A using highly stereoselective vinylogous Mukaiyama aldol reaction
Ramesh, Palakuri,Meshram, Harshadas Mitaram
, p. 9289 - 9292 (2012)
A synthetic approach for the total synthesis of salinipyrone A has been developed. Key steps involve the TiCl4-mediated vinylogous Mukaiyama aldol reaction (VMAR) of chiral ketene silyl N,O-acetal with propionaldyhyde, an aldol condensation, Witting olefination, and a cyclization. The synthesis proceeds in eight steps.