140411-01-4

Basic information

• Product Name: 3-{(1Z,5Z,9Z,14Z)-18-(2-Methoxycarbonyl-ethyl)-13-(1-methoxy-ethyl)-8-[1-(4-methoxy-phenyl)-ethyl]-3,7,12,17-tetramethyl-22,24-dihydro-porphin-2-yl}-propionic acid methyl ester
• CAS NO: 140411-01-4
• Molecular Weight: 730.904
• Mol File: 140411-01-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-{(1Z,5Z,9Z,14Z)-18-(2-Methoxycarbonyl-ethyl)-13-(1-methoxy-ethyl)-8-[1-(4-methoxy-phenyl)-ethyl]-3,7,12,17-tetramethyl-22,24-dihydro-porphin-2-yl}-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{(1Z,5Z,9Z,14Z)-18-(2-Methoxycarbonyl-ethyl)-13-(1-methoxy-ethyl)-8-[1-(4-methoxy-phenyl)-ethyl]-3,7,12,17-tetramethyl-22,24-dihydro-porphin-2-yl}-propionic acid methyl ester(140411-01-4)
• EPA Substance Registry System: 3-{(1Z,5Z,9Z,14Z)-18-(2-Methoxycarbonyl-ethyl)-13-(1-methoxy-ethyl)-8-[1-(4-methoxy-phenyl)-ethyl]-3,7,12,17-tetramethyl-22,24-dihydro-porphin-2-yl}-propionic acid methyl ester(140411-01-4)

Safety Data

• Hazardous Substances Data: 140411-01-4(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 100-66-3 methoxybenzene 
• 5522-66-7 protoporphyrin IX dimethyl ester 

Relevant articles and documents

Natural Tetrapyrrol Derivatives for the Photodynamic Therapy, 2. - Model Reactions for Direct C-C Linkages of Porphyrins

Until now, there is a lack of information about the structure of the active components in the diagnosis and photodynamic therapy of cancer with hematoporphyrin derivatives (HPD).We describe the formation of HPD in terms of benzyl cation chemistry.Selective formation of the C-C-linked model compounds 4, 5 by reaction of protoporphyrin dimethyl ester (2) with electron-rich aromatic compounds as well as of 9-12, 15-17, obtained by reaction of the porphyrin dimethyl esters 2, 6, 7, and 8 with carbon electrophiles (preformed Mannich salts), results from this concept. K ey Words: Photodynamic therapy (PDT) / Porphyrins / Hematoporphyrin derivative (HPD) / Mannich bases / Benzyl cations