14048-09-0Relevant articles and documents
Cyano Modification on Uridine Decreases Base-Pairing Stability and Specificity through Neighboring Disruption in RNA Duplex
Mao, Song,Ranganathan, Srivathsan V.,Tsai, Hsu-Chun,Haruehanroengra, Phensinee,Shen, Fusheng,Valsangkar, Vibhav A.,Han, Bo,Hassan, Abdalla E. A.,Chen, Alan,Sheng, Jia
, p. 2558 - 2565 (2018)
5-Cyanomethyluridine (cnm5U) and 5-cyanouridine (cn5U), the two uridine analogues, were synthesized and incorporated into RNA oligonucleotides. Base-pairing stability and specificity studies in RNA duplexes indicated that cnm5/