14056-88-3Relevant articles and documents
The coordination chemistry of sulfonyl-substituted thioureas towards the d8 metal centres platinum(II), palladium(II), nickel(II) and gold(III)
Henderson, William,Risi, Matthew C.,Saunders, Graham C.
, (2021/07/13)
Reactions of the complexes cis-[PtCl2(PPh3)2], [PtCl2(dppp)] (dppp = Ph2P(CH2)3PPh2), [MCl2(dppe)] (dppe = Ph2P(CH2)2PPh2, M = Ni, Pd), [PdCl2(bipy)] (bipy = 2,2′-bipyridine) and [AuCl2(bp)] (bp = cyclometallated 2-benzylpyridine) with p-TolSO2NHC(S)NHPh and Et3N in refluxing methanol gave a series of new thiourea complexes containing the ligand bound as a dianion through the S and the NPh groups. The related thioureas RSO2NHC(S)NHPh (R = Me, Et) and p-TolSO2NHC(S)NHCH2CH=CH2 were also reacted with cis-[PtCl2(PPh3)2] to form the corresponding complexes [Pt{RSO2NC(S)NPh}(PPh3)2] and [Pt{TolSO2NC(S)NCH2CH=CH2}(PPh3)2] respectively. X-ray structure determinations were carried out on the thiourea MeSO2NHC(S)NHPh and its platinum complex [Pt{MeSO2NC(S)NPh}(PPh3)2], as well as [Pt{TolSO2NC(S)NPh}(PPh3)2]. Both complexes form the distal isomer with a remote NSO2R group, and no evidence was observed for isomerisation of these platinum complexes in solution. The palladium complexes [Pd{TolSO2NC(S)NPh}L2] [L2 = Ph2PCH2CH2PPh2 (dppe), or 2,2′-bipyridine (bipy)] undergo decomposition in solution to form the sulfide-bridged aggregates [Pd3S2(L2)3]2+, identified by ESI MS and 31P NMR.
Pyrrole thioamide complexes of the d8 metals platinum(II), palladium(II) and gold(III)
Tang, Haiming,Saunders, Graham C.,Ma, Xiaochuan,Henderson, William
, (2019/12/09)
Reactions of the cycloaurated gold(III) complexes [AuCl2(2-benzylpyridyl)] and [AuCl2(C6H4CH2NMe2)] with a set of pyrrole-2-thioamide ligands, containing various substituents on the pyrrole ring, gave a series of new gold(III) pyrrole thioamide complexes. X-ray crystal structures on two complexes indicate that the pyrrole thioamide ligand is coordinated through the deprotonated pyrrole nitrogen, as well as the sulfur atom of the deprotonated thioamide group, forming five-membered chelate ring complexes. In both complexes, the two highest trans-influence donor atoms (C and S) are mutually cis. Related sets of platinum(II) and palladium(II) pyrrole thioamide complexes were similarly prepared by reactions of cis-[PtCl2(PPh3)2] and [PdCl2(dppe)] (dppe = Ph2PCH2CH2PPh2)] respectively. The complexes were characterised by NMR and IR spectroscopies, and ESI mass spectrometry. A preliminary investigation of the activity of a selection of compounds towards A549 (adenocarcinomic human alveolar basal epithelial) cells was also carried out.
From NHC to Imidazolyl Ligand: Synthesis of Platinum and Palladium Complexes d10-[M(NHC)2] (M = Pd, Pt) of the NHC 1,3-Diisopropylimidazolin-2-ylidene
Hering, Florian,Radius, Udo
, p. 3236 - 3245 (2016/01/15)
The widely held belief that N-heterocyclic carbenes (NHCs) act only as innocent spectator ligands is not always accurate, even in the context of well-explored reactions. Ligand exchange in the conversion of [Pt(PPh3)2(I2-C2H4)] (3) to [Pt(iPr2Im)2] (2) depends critically on the particular reaction conditions employed, with slight changes leading to vastly different outcomes. In addition to [Pt(iPr2Im)2] (2), complexes [Pt(iPr2Im)(PPh3)(I2-C2H4)] (5) and trans-[Pt(iPr2Im)2(iPr-Im)(H)] (6) were isolated and in the case of 6 fully characterized. Complex 5 represents the first mixed-olefin complex in transition metal chemistry containing both an NHC and a phosphine ligand. Chemical degradation of the NHC was shown to yield the new imidazole-2-yl iPr-Im? in 6. Therefore, the synthesis of [Pt(iPr2Im)2] (2) via metallic reduction of the ionic precursor [Pt(iPr2Im)3(Cl)]+Cl- (9) is favorable, a procedure adaptable to analogous palladium compounds. While [Pd(iPr2Im)3(Cl)]+Cl- (8) is the only product obtained from the reaction of iPr2Im and PdCl2, neutral [Pt(iPr2Im)2(Cl)2] (10), formed as a mixture of its two stereoisomers cis-10 and trans-10, is available through precise control of the stoichiometry in the reaction of PtCl2 and exactly 2 equiv of iPr2Im.
