140635-77-4

Basic information

• Product Name: 3-Oxetanemethanol, 3-methyl-, 4-nitrobenzoate
• CAS NO: 140635-77-4
• Molecular Formula: C12H13NO5
• Molecular Weight: 251.239
• Mol File: 140635-77-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-Oxetanemethanol, 3-methyl-, 4-nitrobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Oxetanemethanol, 3-methyl-, 4-nitrobenzoate(140635-77-4)
• EPA Substance Registry System: 3-Oxetanemethanol, 3-methyl-, 4-nitrobenzoate(140635-77-4)

Safety Data

• Hazardous Substances Data: 140635-77-4(Hazardous Substances Data)

Upstream product

• 3143-02-0 3-hydroxymethyl-3-methyloxethane 
• 122-04-3 4-nitro-benzoyl chloride 
• 62-23-7 4-nitro-benzoic acid 
• 100-09-4 4-methoxybenzoic acid 

Downstream Products

• 140635-78-5 3-methyl-3-(4-aminobenzoyloxymethyl)oxetane 
• 497870-47-0 4-methyl-1-(4-nitrophenyl)-2,6,7-trioxabicyclo[2.2.2]octane 
• 140635-79-6 3-methyl-3-(4-amino-3,5-dibromobenzoyloxymethyl)oxetane 
• 140635-80-9 3-bromo-2-(hydroxymethyl)-2-methyl-n-propyl 4-amino-3,5-dibromobenzoate 
• 140635-81-0 3-methyl-3-(4-trifluoroacetamidobenzoyloxymethyl)oxetane 
• 72116-56-4 3-(methylthio)-6-(4-nitrophenyl)-1,2,4,5-tetrazine 

Relevant articles and documents

REAGENTS AND METHODS FOR TETRAZINE SYNTHESIS

Disclosed herein are mono- and di-substituted tetrazines and methods of their preparation and converting an oxetanyl ester to a thio-substituted tetrazine, which is then converted to a mono-substituted tetrazine, a di-substituted tetrazine, or a vinylether disubstituted tetrazine.

Isomerization of cyclic ethers having a carbonyl functional group: New entries into different heterocyclic compounds

Oxiranes (epoxides) and oxetanes having a carbonyl functional group are chemoselectively isomerized to different heterocyclic compounds via Lewis acid-promoted 1,6- and 1,7-intramolecular nucleophilic attacks of the carbonyl oxygen on the electron-deficient carbon neighboring the oxonium oxygen: for example, cyclic imides to bicyclic acetals, esters to bicyclic orthoesters, sec-amides to 4,5-dihydrooxazole or 5,6-dihydro-4H-1,3-oxazines, and tert-amides to bicyclic acetals or azetidines. The intramolecular attack of a 1,5-positioned carbonyl oxygen predominantly results in a propagating-end isomerization polymerization. On the other hand, cyclic ethers having a 1,8- or farther positioned carbonyl group undergo conventional ring-opening polymerization. A tetrahydrofuran (oxolane) ring does not open, even with a 1,6-positioned carbonyl group.