14067-87-9

Basic information

• Product Name: N¹-phenyl-N²-(phenylsulfonyl)benzamidine
• Synonyms: N¹-phenyl-N²-(phenylsulfonyl)benzamidine
• CAS NO: 14067-87-9
• Molecular Weight: 336.414
• Mol File: 14067-87-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: N¹-phenyl-N²-(phenylsulfonyl)benzamidine(CAS DataBase Reference)
• NIST Chemistry Reference: N¹-phenyl-N²-(phenylsulfonyl)benzamidine(14067-87-9)
• EPA Substance Registry System: N¹-phenyl-N²-(phenylsulfonyl)benzamidine(14067-87-9)

Safety Data

• Hazardous Substances Data: 14067-87-9(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 98-10-2 benzenesulfonamide 
• 160693-94-7 benzophenone-(O-benzenesulfonyl oxime ) 
• 10520-98-6 N-thiobenzoylbenzenesulfonamide 
• 60-29-7 diethyl ether 
• 4513-25-1 N-phenylsulfonylbenzimidoyl chloride 
• 110966-94-4 N¹,N²-bisphenylsulfonyl-N²-phenylbenzamidine 
• 112277-37-9 4-phenylazophenyl N-phenylsulfonylbenzimidate 
• 112277-36-8 N-[1-(4-Nitro-phenoxy)-1-phenyl-meth-(E)-ylidene]-benzenesulfonamide 
• 938-10-3 phenylsulfonyl azide 
• 636-04-4 N-Phenylbenzothioamide 
• 87222-87-5 1-(3-indolyl)-2-phenylsulfonylbenzimidoyl-1,2-dihydroisoquinoline 

Downstream Products

• 100-47-0 benzonitrile 
• 122-39-4 diphenylamine 
• 82719-92-4 N-Phenylimide of N-(Phenylsulfonyl)benzimidic Acid 
• 82719-87-7 N²-Phenylsulfonyl-N¹-phenyl-N¹-benzoylbenzamidine 

Relevant articles and documents

Sulfonyl azides acylsulfonamide derivatives and their use for production of derivative.

PROBLEM TO BE SOLVED: To provide a click reaction having bioorthogonality and high versatility.SOLUTION: Sulfonyl amidines and acylsulfonamides are manufactured by using thioamide and sulfonyl azide. The reaction is a novel click reacting having no need of additives and bioorthogonality and high versatility with proceeding under a mild condition and in a solution.

REACTIONS OF IMIDIC ACID DERIVATIVES WITH NUCLEOPHILIC REAGENTS. BIFUNCTIONAL CATALYSIS OF THE ARYLAMINOLYSIS OF ARYL N-PHENYLSULFONYLBENZIMIDATES IN CHLOROBENZENE

The kinetics of the reaction of aryl N-phenylsulfonylbenzimidates PhC(OArX)=NSO2Ph with aniline in chlorobenzene at 25 deg C are characterized by first-order in the imidate and third and fourth order in the arylamine.The reaction is accelerated by phenols, pyridines, acetic acid, and 2-hydroxypyridines and is described by a kinetic equation of first order in each of the reagents and in the catalyst (in the monomeric form).The catalytic activity of the ring-substituted 2-hydroxypyridines does not depend on the nature of the substituent.This fact and the high activity of the acetic acid and 2-hydroxypyridines compared with the monofunctional compounds are explained by a bifunctional mechanism of catalysis.

REACTIVITY OF N-SUBSTITUTED BENZIMIDOYL CHLORIDES WITH ANILINE IN BENZENE

The kinetics of the reaction of N-substituted benzimidoyl chlorides C6H5C(Cl)=NR with aniline in benzene at 25 deg C were studied.The results were compared with the reactivity of benzoyl chloride C6H5C(Cl)=O and thiobenzoyl chloride C6H5C(Cl)=S.On the basis of the high sensitivity of the process to the introduction of a substituent R at the nitrogen atom in the imidoyl chloride molecule it is concluded that the C=N bond takes part as "reactant" in a nucleophilic substitution mechanism.