14067-99-3

Basic information

• Product Name: N-[(4-bromophenyl)sulfonyl]benzamide
• CAS NO: 14067-99-3
• Molecular Formula: C₁₃H₁₀BrNO₃S
• Molecular Weight: 340.1924
• Mol File: 14067-99-3.mol
• Article Data: 6

Chemical Properties

• Density: 1.577g/cm³
• Refractive Index: 1.626
• CAS DataBase Reference: N-[(4-bromophenyl)sulfonyl]benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(4-bromophenyl)sulfonyl]benzamide(14067-99-3)
• EPA Substance Registry System: N-[(4-bromophenyl)sulfonyl]benzamide(14067-99-3)

Safety Data

• Hazardous Substances Data: 14067-99-3(Hazardous Substances Data)

Upstream product

• 93-99-2 benzoic acid phenyl ester 
• 701-34-8 4-bromo-benzenesulfonic acid amide 
• 65-85-0 benzoic acid 
• 55-21-0 benzamide 
• 98-58-8 4-bromobenzenesulfonyl chloride 
• 98-88-4 benzoyl chloride 
• 6647-76-3 p-bromobenzenesulfonyl azide 

Downstream Products

• 690259-71-3 2-benzyloxy-[1,1';2',1]terphenyl-4-sulfonic acid (1-phenyl-methanoyl)-amide 

Relevant articles and documents

N-Sulfonyl acetylketenimine as a highly reactive intermediate for synthesis of N-Aroylsulfonamides

A highly reactive intermediate N-sulfonyl acetylketenimine was generated from an ynone-participated CuAAC/ring-opening method. Its unique structure allowed it to react with aryl carboxylic acids to give N-aroylsulfonamides via a novel Mumm-type rearrangement.

Catalytic activity of magnetic Fe3O4@Diatomite earth and acetic acid for the N-acylation of sulfonamides

The Br?nsted and Lewis acidic promoted N-acylation of sulfonamides with acetic anhydride or benzoyl chloride has been achieved using glacial acetic acid and magnetic Fe3O4@Diatomite earth. Use of acetic acid as solvent omits the need for organic bases and permits the isolation of products by filtration and precipitation. Additionally, the magnetic composite Fe3O4@Diatomite acts as a conjugate proton super acid, enabling the acylation of sulfonamide compounds.

AMINOALCOHOL DERIVATIVES

The present invention relates to a compound formula [I]: wherein Y is bond,--O--(CH2)n--(in which n is 1, 2, 3 or 4), etc., Z is cyano, tetrazolyl, etc., R1 is hydrogen, lower alkyl, etc., R2 is hydrogen or an amino protective group, R3 is hydrogen or lower alkyl, R4 is hydrogen or lower alkyl, R5 and R8 are each independently hydrogen, halogen, hydroxy, lower alkyl, etc., R6 is hydrogen, lower alkyl, etc., R9 is hydrogen or lower alkyl, and i is 1 or 2, or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiurea or urinary incontinence.