140696-57-7

Basic information

• Product Name: Benzoic acid (R)-((S)-2-benzoyl-6,7-dimethoxy-1,2-dihydro-isoquinolin-1-yl)-(3,4-dimethoxy-phenyl)-methyl ester
• Synonyms: Benzoic acid (R)-((S)-2-benzoyl-6,7-dimethoxy-1,2-dihydro-isoquinolin-1-yl)-(3,4-dimethoxy-phenyl)-methyl ester
• CAS NO: 140696-57-7
• Molecular Weight: 565.623
• Mol File: 140696-57-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid (R)-((S)-2-benzoyl-6,7-dimethoxy-1,2-dihydro-isoquinolin-1-yl)-(3,4-dimethoxy-phenyl)-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid (R)-((S)-2-benzoyl-6,7-dimethoxy-1,2-dihydro-isoquinolin-1-yl)-(3,4-dimethoxy-phenyl)-methyl ester(140696-57-7)
• EPA Substance Registry System: Benzoic acid (R)-((S)-2-benzoyl-6,7-dimethoxy-1,2-dihydro-isoquinolin-1-yl)-(3,4-dimethoxy-phenyl)-methyl ester(140696-57-7)

Safety Data

• Hazardous Substances Data: 140696-57-7(Hazardous Substances Data)

Upstream product

• 135574-68-4 (4R,5R)-4,5-Bis-(3,4-dimethoxy-phenyl)-[1,3,2]dioxathiolane 2,2-dioxide 
• 135574-16-2 (4R,5R)-4,5-Bis-(3,4-dimethoxy-phenyl)-[1,3,2]dioxathiolane 2-oxide 
• 135574-15-1 (2R*,3R*)-2,3-bis(3,4-dimethoxyphenyl)oxirane 
• 135574-17-3 (1R,2S)-2-(2,2-Dimethoxy-ethylamino)-1,2-bis-(3,4-dimethoxy-phenyl)-ethanol 
• 98-88-4 benzoyl chloride 

Downstream Products

• 135574-18-4 Benzoic acid (R)-((S)-2-benzoyl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinolin-1-yl)-(3,4-dimethoxy-phenyl)-methyl ester 
• 15248-39-2 6,7-dimethoxyisoquinoline 
• 58-74-2 Papaverine 

Relevant articles and documents

Short-cut in the pomeranz-fritsch synthesis of 1-benzyl-isoquinolines; short and efficient syntheses of norrecticuline derivatives and of papaverine

A new methodology for the Pomeranz-Fritsch synthesis of 1-benzyl-1,2-dihydroisoquinolines avoiding pavine or isopavine troubles, has been developed. These intermediates could be reduced to their 1,2,3,4-tetrahydro congeners or aromatized to give isoquinolines, as it was demonstrated by the synthesis of some norrecticuline derivatives 4-7 and of papaverin 8.