1408378-64-2Relevant articles and documents
Decarboxylative alkylation of β-keto Acids with isochromans under oxidative conditions
Chen, Yan,Tian, Shi-Kai
supporting information, p. 37 - 39 (2013/08/24)
An unprecedented decarboxylative alkylation reaction of β-keto acids with isochromans has been developed under oxidative conditions. A range of β-keto acids smoothly undergo decarboxylative alkylation with isochromans in the presence of 2,2,6,6-tetramethylpiperdine-1-oxoammonium hexafluorophosphate to give structurally diverse 1-acylmethylisochromans in moderate to excellent yields with extremely high regioselectivity. A range of β-keto acids smoothly undergo decarboxylative alkylation with isochromans in the presence of 2,2,6,6-tetramethylpiperdine-1-oxoammonium hexafluorophosphate to give structurally diverse 1-acylmethylisochromans in moderate to excellent yields. Copyright