140859-04-7

Basic information

• Product Name: 1-<2-C-cyano-2-deoxy-5-O-(dimethoxytrityl)-β-D-arabinofuranosyl>thymine
• Synonyms: 1-<2-C-cyano-2-deoxy-5-O-(dimethoxytrityl)-β-D-arabinofuranosyl>thymine
• CAS NO: 140859-04-7
• Molecular Weight: 569.614
• Mol File: 140859-04-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-<2-C-cyano-2-deoxy-5-O-(dimethoxytrityl)-β-D-arabinofuranosyl>thymine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-<2-C-cyano-2-deoxy-5-O-(dimethoxytrityl)-β-D-arabinofuranosyl>thymine(140859-04-7)
• EPA Substance Registry System: 1-<2-C-cyano-2-deoxy-5-O-(dimethoxytrityl)-β-D-arabinofuranosyl>thymine(140859-04-7)

Safety Data

• Hazardous Substances Data: 140859-04-7(Hazardous Substances Data)

Upstream product

• 1060669-35-3 Thiocarbonic acid O-[(2R,3aR,9aR)-3-cyano-5,5,7,7-tetraisopropyl-2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl] ester O-phenyl ester 
• 140858-90-8 1-<2-C-cyano-2-deoxy-3,5-O-(tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl>thymine 
• 119410-98-9 1-<3,5-O-(tetraisopropyldisiloxane-1,3-diyl)-β-D-erythro-pentofuran-2-ulosyl>-5-methyluracil 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 140858-91-9 1-(2-C-cyano-2-deoxy-β-D-arabinofuranosyl)thymine 

Downstream Products

• 140859-06-9 2'-C-cyano-2',3'-didehydro-2',3'-dideoxy-5'-O-(dimethoxytrityl)-5-methyluridine 

Relevant articles and documents

Nucleosides and nucleotides. 122. 2'-C-cyano-2'-deoxy-1-β-D- arabinofuranosylcytosine and its derivatives. A new class of nucleoside with a broad antitumor spectrum

Design, synthesis, and tumor cell growth inhibitory effects of 2'-C- cyano-2'-deoxy-1-β-D-arabinofuranosyl derivatives of cytosine (1i, CNDAC), thymine (6a), uracil (6c), and adenine (6d) have been described. The synthesis of the target compounds was achi