140865-97-0 Usage
Description
1-(8-hydroxy-3,4-dihydroisoquinolin-2(1H)-yl)ethanone is an organic compound characterized by its off-white solid appearance. It is a derivative of isoquinoline, a type of heterocyclic compound with a fused benzene and pyridine ring structure. The presence of a hydroxyl group at the 8-position and the ethanone functional group attached to the 1-position contribute to its unique chemical properties and potential applications.
Uses
Used in Pharmaceutical Industry:
1-(8-hydroxy-3,4-dihydroisoquinolin-2(1H)-yl)ethanone is used as an intermediate in the synthesis of tetrahydroisoquinoline derivatives, which are important in the development of various pharmaceutical compounds. These derivatives have been found to possess a range of biological activities, including potential applications in the treatment of neurological disorders, cardiovascular diseases, and as analgesics.
Used in Chemical Synthesis:
1-(8-hydroxy-3,4-dihydroisoquinolin-2(1H)-yl)ethanone serves as a key building block in the synthesis of more complex organic molecules. Its unique structure allows for further functionalization and modification, making it a valuable component in the creation of novel compounds with potential applications in various industries, such as materials science, agrochemicals, and pharmaceuticals.
Used in Research and Development:
Due to its unique chemical properties and potential for further modification, 1-(8-hydroxy-3,4-dihydroisoquinolin-2(1H)-yl)ethanone is also utilized in research and development settings. Scientists and chemists can explore its reactivity, stability, and potential interactions with other molecules, leading to the discovery of new compounds and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 140865-97-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,0,8,6 and 5 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 140865-97:
(8*1)+(7*4)+(6*0)+(5*8)+(4*6)+(3*5)+(2*9)+(1*7)=140
140 % 10 = 0
So 140865-97-0 is a valid CAS Registry Number.
140865-97-0Relevant articles and documents
Tyrosine Kinase Inhibitor And Uses Thereof
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Paragraph 0459-0460, (2017/05/15)
Disclosed is a compound of Formula (I) or a pharmaceutically acceptable salt, ester, or solvate thereof, or their stereoisomers, which can be used as tyrosine kinase inhibitor. Also disclosed is a method for preparing the compound, a pharmaceutical composition and a kit comprising the compound, and uses of the compound. The compound can be used as tyrosine kinase inhibitor, or can be used to reduce or inhibit activity of EGFR or mutant thereof, such as EGFR mutant comprising T790M mutation, in a cell, or to treat and/or prevent a disease associated with overactivity of EGFR, such as cancer.
