140866-79-1

Basic information

• Product Name: [4-((2S,5R)-5-Isopropyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-ylmethyl)-benzyl]-phosphonic acid dimethyl ester
• Synonyms: [4-((2S,5R)-5-Isopropyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-ylmethyl)-benzyl]-phosphonic acid dimethyl ester
• CAS NO: 140866-79-1
• Molecular Weight: 396.423
• Mol File: 140866-79-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [4-((2S,5R)-5-Isopropyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-ylmethyl)-benzyl]-phosphonic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [4-((2S,5R)-5-Isopropyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-ylmethyl)-benzyl]-phosphonic acid dimethyl ester(140866-79-1)
• EPA Substance Registry System: [4-((2S,5R)-5-Isopropyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-ylmethyl)-benzyl]-phosphonic acid dimethyl ester(140866-79-1)

Safety Data

• Hazardous Substances Data: 140866-79-1(Hazardous Substances Data)

Upstream product

• 109838-85-9 (2R)-2,5-dihydro-2-isopropyl-3,6-dimethoxypyrazine 
• 140866-78-0 (4-bromo-methylbenzyl)phosphonic acid dimethyl ester 

Downstream Products

• 106391-85-9 (R)-methyl 2-((tert-butoxycarbonyl)amino)-3-methylbutanoate 
• 140866-81-5 (S)-2-tert-Butoxycarbonylamino-3-[4-(dimethoxy-phosphorylmethyl)-phenyl]-propionic acid methyl ester 
• 140866-83-7 (S)-2-{(R)-2-tert-Butoxycarbonylamino-3-[4-(dimethoxy-phosphorylmethyl)-phenyl]-propionylamino}-4-methyl-pentanoic acid methyl ester 
• 140866-83-7 (S)-2-{(S)-2-tert-Butoxycarbonylamino-3-[4-(dimethoxy-phosphorylmethyl)-phenyl]-propionylamino}-4-methyl-pentanoic acid methyl ester 
• 140866-82-6 N-t-Boc-p-dimethylphosphonomethyl-L-phenylalanine 
• 7146-15-8 D-Valine methyl ester hydrochloride 
• 140866-80-4 p-dimethylphosphonomethyl-L-phenylalanine methyl ester hydrochloride 

Relevant articles and documents

Synthesis of p-phosphonomethyl-L-phenylalanine using camphor sultam or D-valine as chiral auxiliaries and its incorporation into integrin sequences.

The synthesis of N-Boc-p-phosphonomethyl-L-phenylalanine with two different chiral auxiliaries, camphor sultam or D-valine is described. The preparations have essentially identical properties and have been used to incorporate the amino acid into two integrin peptides as non-hydrolyzable isosteres of phosphotyrosine.