14087-90-2Relevant articles and documents
2-Aminotetralones: Novel inhibitors of MurA and MurZ
Dunsmore, Colin J.,Miller, Keith,Blake, Katy L.,Patching, Simon G.,Henderson, Peter J.F.,Garnett, James A.,Stubbings, William J.,Phillips, Simon E.V.,Palestrant, Deborah J.,Angeles, Joseph De Los,Leeds, Jennifer A.,Chopra, Ian,Fishwick, Colin W.G.
, p. 1730 - 1734 (2008/12/20)
Several 2-aminotetralones were identified as novel inhibitors of the bacterial enzymes MurA and MurZ. A number of these inhibitors demonstrated antibacterial activity against Staphylococcus aureus and Escherichia coli with MICs in the range 8-128 μg/ml. B