141034-17-5

Basic information

• Product Name: 1-{(2Z)-3-[(1R,2R)-2-hydroxy-1,2,3,4-tetrahydronaphthalen-1-yl]-2-imino-1,3-thiazolidin-5-yl}ethanone
• CAS NO: 141034-17-5
• Molecular Formula: C₁₅H₁₈N₂O₂S
• Molecular Weight: 290.3806
• Mol File: 141034-17-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 470.2°C at 760 mmHg
• Flash Point: 238.2°C
• Density: 1.42g/cm³
• Vapor Pressure: 1.21E-09mmHg at 25°C
• Refractive Index: 1.702
• CAS DataBase Reference: 1-{(2Z)-3-[(1R,2R)-2-hydroxy-1,2,3,4-tetrahydronaphthalen-1-yl]-2-imino-1,3-thiazolidin-5-yl}ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{(2Z)-3-[(1R,2R)-2-hydroxy-1,2,3,4-tetrahydronaphthalen-1-yl]-2-imino-1,3-thiazolidin-5-yl}ethanone(141034-17-5)
• EPA Substance Registry System: 1-{(2Z)-3-[(1R,2R)-2-hydroxy-1,2,3,4-tetrahydronaphthalen-1-yl]-2-imino-1,3-thiazolidin-5-yl}ethanone(141034-17-5)

Safety Data

• Hazardous Substances Data: 141034-17-5(Hazardous Substances Data)

Upstream product

• 141034-11-9 trans-N-(2-hydroxy-1,2,3,4-tetrahydronaphthalene-1-yl)-N'-benzoyl thiourea 
• 141034-13-1 trans-N-(2-hydroxy-1,2,3,4-tetrahydronaphthalene-1-yl) thiourea 
• 7480-36-6 (+/-)-trans-1-amino-2-hydroxy-1,2,3,4-tetrahydronaphthalene 
• 108-24-7 acetic anhydride 
• 141034-15-3 trans-2-iminothiazolidine 

Relevant articles and documents

SYNTHESIS OF trans-2-IMINOTHIAZOLIDINE AND RELATED COMPOUNDS - A NEW CLASS OF ANTIDEPRESSANTS

Antiparasitic and antidepressant activities exhibited by tetramisole (I) and its enantiomers prompted the study of its structural analogs trans-2-iminothiazolidine (VIII/IX) and 2,3,4a,5,6,10b-hexahydronaphthoimidazothiazole (XII), 2,3,4a,5-tetrahydro-9bH-indenoimidazothiazole (XIII), and 2,3,4a,5-tetrahydro-9bH-indenoimidazothiazole (XVI), and a homolog 3,4,6,7-tetrahydro-7-phenyl-2H-imidazo-1,3-thiazine (XX).While none of these compounds showed any noteworthy antiparasitic activity, the trans-2-iminothiazolidine (VIII) has shown marked antidepressant activity, better than imipramine in the tests used, and provides a new structural lead for antidepressants.