141079-91-6

Basic information

• Product Name: (R)-3-((S)-4-Fluoro-benzenesulfinyl)-butyric acid
• Synonyms: (R)-3-((S)-4-Fluoro-benzenesulfinyl)-butyric acid
• CAS NO: 141079-91-6
• Molecular Weight: 230.26
• Mol File: 141079-91-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3-((S)-4-Fluoro-benzenesulfinyl)-butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-((S)-4-Fluoro-benzenesulfinyl)-butyric acid(141079-91-6)
• EPA Substance Registry System: (R)-3-((S)-4-Fluoro-benzenesulfinyl)-butyric acid(141079-91-6)

Safety Data

• Hazardous Substances Data: 141079-91-6(Hazardous Substances Data)

Upstream product

• 371-42-6 4-Fluorothiophenol 
• 141079-82-5 (R)-3-(4-Fluoro-phenylsulfanyl)-butyric acid 

Relevant articles and documents

Preparation of stereoisomers of 3-sulfinylbutyric acid from (R)- and (S)-4-methyl-2-oxetanone

The β-lactone ((S) and (R)-4-methyl-2-oxetanone, 1, ent-1), readily available from (R)- and (S)-3-hydroxybutyric acid, is opened by sodium hydrosulfide, sodium alkane- and arenethiolates, respectively, with inversion of configuration. The resulting 3-(alkylthio)-2f, 2g, and 3-(arylthio)butyric acids, 2b-2e, ent-2h-2k (Table 1), oxidized with hydrogen peroxide in acetone to give the corresponding 3-(alkylsulfinyl)- and 3-(arylsulfinyl)butyric acids as mixtures of diastereoisomers 3b-3k and 4b-4k. These are separated and the pure like and unlike diastereoisomers isolated and fully characterized (Table 4). Configurational assignments rest upon a crystal structure analysis and comparison of properties in the two series.