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141120-33-4

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141120-33-4 Usage

Chemical structure

1,4-dioxaspiro[4.5]decan-8-yl methanesulfonate

Type of compound

Sulfonate ester

Derived from

1,4-dioxaspiro[4.5]decan-8-ol

Common use

Pharmaceutical intermediate in the synthesis of various medications

Known for

Stabilizing and protecting drugs by preventing degradation and improving shelf life

Utilized as

Blocking agent for the protection of hydroxy and amino groups in organic synthesis

Applications

Pharmaceutical and chemical industries

Versatility

Wide range of applications in both industries due to its protective and stabilizing properties

Check Digit Verification of cas no

The CAS Registry Mumber 141120-33-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,1,2 and 0 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 141120-33:
(8*1)+(7*4)+(6*1)+(5*1)+(4*2)+(3*0)+(2*3)+(1*3)=64
64 % 10 = 4
So 141120-33-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H16O5S/c1-15(10,11)14-8-2-4-9(5-3-8)12-6-7-13-9/h8H,2-7H2,1H3

141120-33-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,4-dioxaspiro[4.5]decan-8-yl methanesulfonate

1.2 Other means of identification

Product number -
Other names AB3686

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:141120-33-4 SDS

141120-33-4Relevant articles and documents

Synthesis of 1-substituted epibatidine analogues and their in vitro and in vivo evaluation as α4β2 nicotinic acetylcholine receptor ligands

Heugebaert, Thomas S.A.,Van Overtveldt, Melissa,De Blieck, Ann,Wuyts, Benjamin,Augustijns, Patrick,Ponce-Gamez, Eugenia,Rivera, Alicia,De Groote, Dominic,Lefebvre, Romain A.,Wouters, Patrick,Meert, Theo,Devulder, Jacques,Stevens, Christian V.

, p. 2226 - 2234 (2014)

The highly potent natural alkaloid epibatidine remains a source of inspiration in the search for new analgesic drugs. In this paper, we describe an expansion of our previously reported synthesis of epibatidine analogues, and five synthetic alkaloids chara

3-(dimethylaminomethyl) cyclohex-4-alcohol derivative as well as preparation method and pharmaceutical application thereof

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Paragraph 0292-0295, (2021/05/08)

The invention belongs to the field of pharmacy, and relates to a 3-(dimethylaminomethyl) cyclohex-4-alcohol derivative with a general formula (I) or a salt thereof and a preparation method, and relates to an application of the compound in treatment of opioid receptor mediated diseases. The present invention provides a pharmaceutically acceptable solvate or hydrate of a compound of formula (I), and also provides a pharmaceutical composition comprising: a compound of formula (I) or a pharmaceutically acceptable salt, solvate or hydrate thereof; and a pharmaceutically acceptable carrier. The medicine prepared from the compound can be used for treating or improving diseases related to an opioid receptor; wherein the diseases can be selected from but not limited to pain, gastrointestinal diseases and depression.

BENZAMIDES OF PYRAZOLYL-AMINO-PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF

-

Paragraph 00719, (2020/07/07)

Provided is a novel class of orally and/or topically available, selective and potent JAK inhibitors as safe and effective therapeutics against various diseases and disorders. More particularly, provided are pharmaceutical composition of these compounds and methods of their preparation and use thereof.

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