141178-00-9

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, 5-acetyl-6-(2-chlorophenyl)-3-(phenylmethyl)-
• CAS NO: 141178-00-9
• Molecular Formula: C19H15ClN2O3
• Molecular Weight: 354.793
• Mol File: 141178-00-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 5-acetyl-6-(2-chlorophenyl)-3-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 5-acetyl-6-(2-chlorophenyl)-3-(phenylmethyl)-(141178-00-9)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 5-acetyl-6-(2-chlorophenyl)-3-(phenylmethyl)-(141178-00-9)

Safety Data

• Hazardous Substances Data: 141178-00-9(Hazardous Substances Data)

Upstream product

• 10128-99-1 3-benzyl-6-methyl-[1,3]oxazine-2,4-dione 
• 609-66-5 2-chlorobenzamide 
• 15717-17-6 2-chlorothiobenzamide 

Relevant articles and documents

Heterocyclic Transformations Part 4: A Facile Transformation of 3-Alkyl-6-methyl-1,3-oxazine-2,4(3H)-diones to 6-Substituted 5-acetyluracils and 6-Thioxo-1,3,5-triazine-2,4(1H,3H,5H)-diones

3-Benzyl-6-methyl-1,3-oxazine-2,4(3H)-dione 1 (R = CH2Ph) reacts under phase-transfer catalytic conditions with amides and thioamides to give 6-substituted 5-acetyluracils and with malonamide to give a bicyclic pyridopyrimidine system.Similar reactions of 1 with thioureas provide 6-thioxo-1,3,5-triazine-2,4(1H,3H,5H)-diones, but with ureas, the substituents influence the mode of the reaction and the nature of the products.The synthetic scope and utility of these reactions has been examined.