141196-69-2 Usage
Description
7-Oxostaurosporine is an oxidized and highly fluorescent analogue of the antibiotics UCN-01 and UCN-02. It is a potent inhibitor of protein kinase C and the formation of cellular blebs induced by phorbols. 7-oxostaurosporine exhibits significant activity against tumor cell lines, similar to that of UCN-01, and plays a crucial role in inhibiting the cell cycle at the G2 stage, leading to the accumulation of 4C DNA cells.
Uses
Used in Pharmaceutical Industry:
7-Oxostaurosporine is used as a potent inhibitor for protein kinase C and cellular bleb formation induced by phorbols. Its application in this industry is due to its ability to inhibit the cell cycle at the G2 stage, which can be beneficial in the development of cancer treatments.
Used in Cancer Research:
7-Oxostaurosporine is used as a compound with significant activity against tumor cell lines, similar to UCN-01. Its application in cancer research is attributed to its potential in providing insights into the development of new cancer therapies and understanding the mechanisms of cell cycle regulation.
Used in Fluorescent Imaging:
As an oxidized and highly fluorescent analogue, 7-Oxostaurosporine is used in the field of fluorescent imaging. Its application in this area is due to its ability to emit fluorescence, which can be useful for visualizing cellular processes and structures in various research and diagnostic applications.
Used in Drug Development:
7-Oxostaurosporine is used as a starting point for the development of new drugs, particularly those targeting protein kinase C and cell cycle regulation. Its application in drug development is based on its potent inhibitory properties and potential to be modified or combined with other compounds to create more effective treatments for various diseases, including cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 141196-69-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,1,9 and 6 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 141196-69:
(8*1)+(7*4)+(6*1)+(5*1)+(4*9)+(3*6)+(2*6)+(1*9)=122
122 % 10 = 2
So 141196-69-2 is a valid CAS Registry Number.
InChI:InChI=1/C28H24N4O4/c1-28-25(35-3)15(29-2)12-18(36-28)31-16-10-6-4-8-13(16)19-21-22(27(34)30-26(21)33)20-14-9-5-7-11-17(14)32(28)24(20)23(19)31/h4-11,15,18,25,29H,12H2,1-3H3,(H,30,33,34)/t15-,18-,25+,28+/m0/s1
