141206-42-0

Basic information

• Product Name: N-Butyl-1-deoxygalactonojirimycin
• Synonyms: N-Butyl-1-deoxygalactonojirimycin;(2R,3S,4R,5S)-1-(But-1-yl)-2-(hydroxymethyl)piperidine-3,4,5-triol;N-(But-1-yl)deoxygalactonojirimycin, (2R,3S,4R,5S)-1-(But-1-yl)-2-(hydroxymethyl)-3,4,5-trihydroxypiperidine;(2R,3S,4R,5S)-1-Butyl-2-(hydroxyMethyl)-3,4,5-piperidinetriol;Lucerastat
• CAS NO: 141206-42-0
• Molecular Formula: C10H21NO4
• Molecular Weight: 219.279
• Product Categories: Glycosidase Inhibitors;Inhibitors
• Mol File: 141206-42-0.mol
• Article Data: 0

Chemical Properties

• Melting Point: 123-124°C
• Boiling Point: 394.7±42.0 °C(Predicted)
• Appearance: /
• Density: 1.234±0.06 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• PKA: 13.72±0.70(Predicted)
• CAS DataBase Reference: N-Butyl-1-deoxygalactonojirimycin(CAS DataBase Reference)
• NIST Chemistry Reference: N-Butyl-1-deoxygalactonojirimycin(141206-42-0)
• EPA Substance Registry System: N-Butyl-1-deoxygalactonojirimycin(141206-42-0)

Safety Data

• Hazardous Substances Data: 141206-42-0(Hazardous Substances Data)

Usage

Description

N-Butyl-1-deoxygalactonojirimycin is a potent and selective α-D-galactosidase inhibitor, which is a white to off-white solid. It acts as a selective inhibitor of GlcCer synthesis, making it a valuable compound in various applications.

Uses

Used in Pharmaceutical Industry:
N-Butyl-1-deoxygalactonojirimycin is used as an enzyme inhibitor for its potent and selective action against α-D-galactosidase. This property makes it a promising candidate for the development of drugs targeting conditions related to the overactivity or abnormal function of this enzyme.
Used in Research Applications:
In the field of research, N-Butyl-1-deoxygalactonojirimycin is used as a tool compound to study the role of α-D-galactosidase and GlcCer synthesis in various biological processes. Its selective inhibition capabilities allow researchers to gain insights into the underlying mechanisms and pathways involving these targets.
Used in Drug Development:
N-Butyl-1-deoxygalactonojirimycin is used as a lead compound in the development of novel therapeutics for diseases where α-D-galactosidase inhibition or modulation of GlcCer synthesis could be beneficial. Its chemical properties and biological activity make it a valuable starting point for designing new drugs with improved efficacy and selectivity.
Used in Biochemical Assays:
N-Butyl-1-deoxygalactonojirimycin is used as a specific inhibitor in biochemical assays to assess the activity of α-D-galactosidase. This allows researchers to accurately measure the enzyme's activity and study its role in various biological processes.
Overall, N-Butyl-1-deoxygalactonojirimycin's unique properties and applications make it a versatile compound with potential uses in various industries, particularly in pharmaceuticals, research, and drug development.