141210-66-4

Basic information

• Product Name: 3-[(dimethylamino)methylene]-1-ethyl-1,3-dihydro-2H-indol-2-one
• Synonyms: 3-[(dimethylamino)methylene]-1-ethyl-1,3-dihydro-2H-indol-2-one
• CAS NO: 141210-66-4
• Molecular Formula: C13H16N2O
• Molecular Weight: 216.27894
• Mol File: 141210-66-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-[(dimethylamino)methylene]-1-ethyl-1,3-dihydro-2H-indol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(dimethylamino)methylene]-1-ethyl-1,3-dihydro-2H-indol-2-one(141210-66-4)
• EPA Substance Registry System: 3-[(dimethylamino)methylene]-1-ethyl-1,3-dihydro-2H-indol-2-one(141210-66-4)

Safety Data

• Hazardous Substances Data: 141210-66-4(Hazardous Substances Data)

Upstream product

• 61-28-9 1-ethyl-1,3-dihydro-2H-indol-2-one 
• 1188-33-6 N,N-dimethylformamide diethyl diacetal 

Relevant articles and documents

LACTAM AND AMIDE ACETALS. 69. SYNTHESIS AND PROPERTIES OF 3-(AMINOMETHYLENE)-2-INDOLINONE DERIVATIVES

Oxindole derivatives reacted with the diethyl acetals of dimethylformamide and dimethylacetamide to give the corresponding derivatives of 3-(aminomethylene)-, (aminoethylidene)-, and (ethoxyethylidene)-2-indolinone.These products were then easily converted to N-aryl- and N-alkylaminomethyleneoxindoles upon treatment with aryl or alkyl amines.The alkylation of N,N-dimethylaminomethylene-2-indolinones by dimethyl sulfate and triethyloxonium tetrafluoroborate, and the reactions of the resulting methyl sulfates and tetrafluoroborates with nucleophilic reagents were studied.The configuration of the 3-(aminomethylene)-2-indolinone derivatives prepared at the enamine C=C double bond was investigated by NMR.The free energies of activation for the cis-trans isomerization were determined in a number of cases.