1412271-47-6

Basic information

• Product Name: C₂₄H₂₅N₂O₂⁽¹⁺⁾*Br^(1-)
• Synonyms: C₂₄H₂₅N₂O₂⁽¹⁺⁾*Br^(1-)
• CAS NO: 1412271-47-6
• Molecular Weight: 453.379
• Mol File: 1412271-47-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₅N₂O₂⁽¹⁺⁾*Br^(1-)(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₅N₂O₂⁽¹⁺⁾*Br^(1-)(1412271-47-6)
• EPA Substance Registry System: C₂₄H₂₅N₂O₂⁽¹⁺⁾*Br^(1-)(1412271-47-6)

Safety Data

• Hazardous Substances Data: 1412271-47-6(Hazardous Substances Data)

Upstream product

• 198707-57-2 3-(2,3-dihydro-1-benzofuran-5-yl)prop-2-enoic acid 
• 1453221-93-6 C₁₁H₁₁ClO 
• 1412272-35-5 dihydrofuranindol 
• 448964-30-5 2,3,5,6-tetrahydro-7H-indeno[5,6-b]furan-7-one 
• 215057-28-6 3-(2,3-dihydro-1-benzofuran-5-yl)propanoic acid 
• 203505-84-4 3-(2,3-dihydro-1-benzofuran-5-yl)-2-propenoic acid 
• 55745-70-5 2,3-dihydro-benzofuran-5-carbaldehyde 
• 496-16-2 2.3-dihydrobenzofuran 
• 1412272-47-9 C₁₆H₁₈N₂O 
• 70-11-1 α-bromoacetophenone 

Relevant articles and documents

Dihydrofuran and yinyin alkane - imidazole salt compound and its preparation method

The invention discloses a series of dihydrofuran indenoane-imidazole salts compounds and a preparation method thereof. The preparation method comprises the following steps of: carrying out Vilsmeier reaction and Perskin reaction on 2,3-dihydrobenzofuran taken as a raw material; reducing palladium/carbon in an acetic acid to 5-propionic acid dihydrobenzofuran and forming acyl chloride with thionyl chloride; carrying out intramolecular Friedel-Crafts reaction and reducing in an alcohol solution by using sodium borohydride to obtain dihydrofuran indenoanol; forming a chloride in a toluene solution with the thionyl chloride; and reflowing and reacting with imidazole or 2-methyl imidazole or 2-ethyl imidazole or benzimidazole in acetonitrile or a toluene solvent to synthesize 1-(dihydrofuran indenoane) imidazole, and reacting with a halide on the above basis to synthesize the compound. According to the dihydrofuran indenoane-imidazole salts compounds and the preparation method thereof, pharmacophores with obvious tumor resisting activity in natural products are used as precursors to carry out designing and synthesizing on anti-tumor medicine molecule, and when an imidazole structure unit in a synthesized compound is the benzimidazole, particularly a naphthoyl methyl imidazole salts compound, the compound has very good in-vitro anticancer physiological activity.