1412405-59-4

Basic information

• Product Name: 2-((5-bromo-4-ethyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-isopropylphenyl)acetamide
• Synonyms: 2-((5-bromo-4-ethyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-isopropylphenyl)acetamide
• CAS NO: 1412405-59-4
• Molecular Weight: 383.312
• Mol File: 1412405-59-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-((5-bromo-4-ethyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-isopropylphenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((5-bromo-4-ethyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-isopropylphenyl)acetamide(1412405-59-4)
• EPA Substance Registry System: 2-((5-bromo-4-ethyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-isopropylphenyl)acetamide(1412405-59-4)

Safety Data

• Hazardous Substances Data: 1412405-59-4(Hazardous Substances Data)

Upstream product

• 99-88-7 4-Isopropylaniline 
• 1527-61-3 α-chloro-N-(p-isopropylphenyl)acetamide 
• 1412405-55-0 2-((5-amino-4-ethyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-isopropylphenyl)acetamide 

Downstream Products

• 1412405-56-1 2-((4-ethyl-5-(2-fluoropyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-isopropylphenyl)acetamide 

Relevant articles and documents

Narrow SAR in odorant sensing Orco receptor agonists

The systematic exploration of a series of triazole-based agonists of the cation channel insect odorant receptor is reported. The structure-activity relationships of independent sections of the molecules are examined. Very small changes to the compound structure were found to exert a large impact on compound activity. Optimal substitutions were combined using a 'mix-and-match' strategy to produce best-in-class compounds that are capable of potently agonizing odorant receptor activity and may form the basis for the identification of a new mode of insect behavior modification.

COMPOSITION FOR INHIBITION OF INSECT SENSING

In one aspect, the invention relates to chemical modulators of insect olfactory receptors. In particular, compounds and compositions are provided that can inhibit sensory (e.g., host targeting) functions in airborne insects such as mosquitos. Method of employing such agents, and articles incorporating the same, are also provided. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.