141293-20-1

Basic information

• Product Name: (1'S,2R,4''S,5''S)-2-[(benzyloxymethyl-2,2-dimethyl-[1,3]-dioxolan-4-yl)hydroxymethyl]-5-oxo-2,5-dihydropyrrole-1-carboxylic acid tert-butyl ester
• Synonyms: (1'S,2R,4''S,5''S)-2-[(benzyloxymethyl-2,2-dimethyl-[1,3]-dioxolan-4-yl)hydroxymethyl]-5-oxo-2,5-dihydropyrrole-1-carboxylic acid tert-butyl ester
• CAS NO: 141293-20-1
• Molecular Weight: 433.502
• Mol File: 141293-20-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (1'S,2R,4''S,5''S)-2-[(benzyloxymethyl-2,2-dimethyl-[1,3]-dioxolan-4-yl)hydroxymethyl]-5-oxo-2,5-dihydropyrrole-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1'S,2R,4''S,5''S)-2-[(benzyloxymethyl-2,2-dimethyl-[1,3]-dioxolan-4-yl)hydroxymethyl]-5-oxo-2,5-dihydropyrrole-1-carboxylic acid tert-butyl ester(141293-20-1)
• EPA Substance Registry System: (1'S,2R,4''S,5''S)-2-[(benzyloxymethyl-2,2-dimethyl-[1,3]-dioxolan-4-yl)hydroxymethyl]-5-oxo-2,5-dihydropyrrole-1-carboxylic acid tert-butyl ester(141293-20-1)

Safety Data

• Hazardous Substances Data: 141293-20-1(Hazardous Substances Data)

Upstream product

• 141293-14-3 N-(tert-butoxycarbonyl)pyrrol-2(5H)-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 81028-12-8 (4S,5R)-4-benzyloxymethyl-2,2-dimethyl-1,3-dioxolane-5-carboxaldehyde 
• 141293-28-9 N-(tert-butoxycarbonyl)-2-[(tert-butyldimethylsilyl)oxy]pyrrole 

Downstream Products

• 161791-63-5 6-O-benzyl-2-(tert-butoxycarbonylamino)-3-O-(tert-butyldimethylsilyl)-2-deoxy-4,5-O-isopropylidene-L-galactonic acid 
• 161791-58-8 6-O-benzyl-2-(tert-butoxycarbonylamino)-3-O-(tert-butyldimethylsilyl)-2-deoxy-4,5-O-isopropylidene-L-galactose 
• 583040-00-0 (1S,2R,3S,7S,8S,9R)-10-benzyl-2,8-bis-(tert-butyldimethylsilanyloxy)-5,5-dimethyl-4,6-dioxa-10-aza-tricyclo[7.2.1.0]dodecan-11-one 
• 583039-97-8 (1'S,2R,4''S,5''S)-2-[(benzyloxymethyl-2,2-dimethyl-[1,3]-dioxolan-4-yl)-(tert-butyldimethylsilanyloxy)methyl]-5-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 583039-98-9 (1'S,4''S,5R,5''S)-1-benzyl-5-[(benzyloxymethyl-2,2-dimethyl-[1,3]-dioxolan-4-yl)-(tert-butyldimethylsilanyloxy)methyl]pyrrolidin-2-one 
• 583040-19-1 (R)-1-Benzyl-5-[(S)-(tert-butyl-dimethyl-silanyloxy)-((4R,5S)-5-hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-methyl]-pyrrolidin-2-one 
• 583040-18-0 (R)-5-[(S)-((4R,5S)-5-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-(tert-butyl-dimethyl-silanyloxy)-methyl]-pyrrolidin-2-one 
• 583039-99-0 (1'S,2''R,4R,5S)-5-[(1-benzyl-5-oxo-pyrrolidin-2-yl)-(tert-butyldimethylsilanyloxy)methyl]-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 583040-17-9 (R)-2-[(S)-((4S,5S)-5-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-5-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 155128-26-0 4-amino-8-O-benzyl-2,3,4-trideoxy-6,7-O-isopropylidene-L-galacto-oct-2-enoic acid 1,4-lactam 
• 161791-54-4 8-O-benzyl-4-(tert-butoxycarbonylamino)-5-O-(tert-butyldimethylsilyl)-2,3,4-trideoxy-6,7-O-isopropylidene-L-galacto-oct-2-enoic acid 1,4-lactam 

Relevant articles and documents

Asymmetric Synthesis of 4-Amino-2,3,4-trideoxyaldonic Acids: Novel GABA C-Glycoconjugates

Stereochemically defined 4-amino-2,3,4-trideoxyaldonic acids 4, representatives of a new progeny of C-glycosylated GABAs, have been synthesized from the readily available aldehydo precursors 1 in three steps and 60-75percent overall yields.The key reactio

General Approach to Hydroxylate α-Amino Acids Exploiting N-(tert-Butoxycarbonyl)-2-(tert-butyldimethylsiloxy)pyrrole

Racemic β-hydroxy-α-amino acids 7a, 7b and 10 of either threo or erythro configuration have been efficiently synthesized from simple aldehydes, utilizing N-(tert-butoxycarbonyl)-2-(tert-butyl-dimethylsiloxy)pyrrole (TBDMSOP) as a glycine-anion equivalent.Similar methodology, employing readily available aldehydo sugar precursors, has been successfully applied to syntheses of enantiomerically pure polyhydroxylated α-amino acids 14a-14f possessing diverse constitution and chirality.

N-(tert-Butoxycarbonyl)-2-(tert-butyldimethylsiloxy)pyrrole: A Promising Compound for Synthesis of Chiral Nonracemic Hydroxylated Pyrrolidine Derivatives

N-t-Boc-2-(tert-butyldimethylsiloxy)pyrrole has been synthesized from pyrrole and used to prepare enantiomerically pure pyrrolinones 5, 6, 15, and 16 and polyhydroxylated pyrrolidinones of type 11 and 12.