141303-28-8

Basic information

• Product Name: Benzenemethanol, a-(chloromethyl)-3-methyl-
• CAS NO: 141303-28-8
• Molecular Formula: C9H11ClO
• Molecular Weight: 170.639
• Mol File: 141303-28-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-(chloromethyl)-3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-(chloromethyl)-3-methyl-(141303-28-8)
• EPA Substance Registry System: Benzenemethanol, a-(chloromethyl)-3-methyl-(141303-28-8)

Safety Data

• Hazardous Substances Data: 141303-28-8(Hazardous Substances Data)

Upstream product

• 100-80-1 3-methylstyrene 
• 593-71-5 Chloroiodomethane 
• 620-23-5 m-tolyl aldehyde 
• 21886-54-4 3-methylphenyl chloromethyl ketone 
• 144222-34-4 (R,R)-N-(p-toluenesulfonyl)-1,2-diphenylethylenediamine 

Relevant articles and documents

Cascade bio-hydroxylation and dehalogenation for one-pot enantioselective synthesis of optically active β-halohydrins from halohydrocarbons

A stereoselective hydroxylation and enantioselective dehalogenation cascade reaction was developed for the synthesis of optically active β-haloalcohols from halohydrocarbons. This cascade system employed P450 and halohydrin dehalogenase as two compatible biocatalysts, allowing a straightforward, greener and efficient access to β-halohydrins with excellent enantioselectivities (98-99%).

PROCESS FOR PRODUCING OPTICALLY ACTIVE HALOHYDRIN COMPOUND

A process of preparing an optically active halohydrin compound characterized by comprising asymmetric hydrogen transfer reduction of an α-haloketone compound in the presence of a group 9 transition metal compound having a substituted or unsubstituted cyclopentadienyl group and an optically active diamine compound. The asymmetric hydrogen transfer reduction is preferably conducted in the presence of a base.