141303-34-6

Basic information

• Product Name: Oxirane, (3,4-dichlorophenyl)-, (2R)-
• CAS NO: 141303-34-6
• Molecular Formula: C8H6Cl2O
• Molecular Weight: 189.041
• Mol File: 141303-34-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Oxirane, (3,4-dichlorophenyl)-, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxirane, (3,4-dichlorophenyl)-, (2R)-(141303-34-6)
• EPA Substance Registry System: Oxirane, (3,4-dichlorophenyl)-, (2R)-(141303-34-6)

Safety Data

• Hazardous Substances Data: 141303-34-6(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 586418-02-2 (R)-1-(3,4-dichlorophenyl)-1,2-ethanediol 
• 2632-10-2 2-bromo-1-(3,4-dichlorophenyl)ethanone 
• 2039-83-0 3,4-dichlorostyrene 

Downstream Products

• 1155304-64-5 (R)-1-(3,4-dichlorophenyl)-2-(2-hydroxyethylamino)ethanol 

Relevant articles and documents

One-pot route to β-adrenergic blockers via enantioselective organocatalysed epoxidation of terminal alkenes as a key step

A convenient and environmentally attractive one-pot two-step process for the synthesis of β-adrenergic blockers via Shi's organocatalytic epoxidation of terminal alkenes and subsequent aminolysis reaction of epoxides with isopropylamine under mild reaction conditions has been developed. This journal is the Partner Organisations 2014.

Biomimetic non-heme iron-catalyzed epoxidation of challenging terminal alkenes using aqueous H2O2 as an environmentally friendly oxidant

Catalysis mediated by iron complexes is emerging as an eco-friendly and inexpensive option in comparison to traditional metal catalysis. The epoxidation of alkenes constitutes an attractive application of iron(III) catalysis, in which terminal olefins are challenging substrates. Herein, we describe our study on the design of biomimetic non-heme ligands for the in situ generation of iron(III) complexes and their evaluation as potential catalysts in epoxidation of terminal olefins. Since it is well-known that active sites of oxidases might involve imidazole fragment of histidine, various simple imidazole derivatives (seven compounds) were initially evaluated in order to find the best reaction conditions and to develop, subsequently, more elaborated amino acid-derived peptide-like chiral ligands (10 derivatives) for enantioselective epoxidations.

HETEROCYCLIC DERIVATIVES AS MODULATORS OF ION CHANNELS

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