141318-79-8

Basic information

• Product Name: R-3,4-Diaminobutyric acid 2HCl
• Synonyms: R-3,4-Diaminobutyric acid 2HCl;(R)-3,4-Diaminobutyric acid dihydrochloride;(R)-3,4-diaminobutanoic acid dihydrochloride;REF DUPL: R-3,4-Diaminobutyric acid 2HCl;(3R)-3,4-diaminobutanoic acid,dihydrochloride
• CAS NO: 141318-79-8
• Molecular Formula: C4H12Cl2N2O2
• Molecular Weight: 191.05628
• Mol File: 141318-79-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 328.1 °C at 760 mmHg
• Flash Point: 152.2 °C
• Appearance: /
• Vapor Pressure: 3.83E-05mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: R-3,4-Diaminobutyric acid 2HCl(CAS DataBase Reference)
• NIST Chemistry Reference: R-3,4-Diaminobutyric acid 2HCl(141318-79-8)
• EPA Substance Registry System: R-3,4-Diaminobutyric acid 2HCl(141318-79-8)

Safety Data

• Hazardous Substances Data: 141318-79-8(Hazardous Substances Data)

Usage

General Description

"R-3,4-Diaminobutyric acid 2HCl" is a chemical compound composed of R-3,4-diaminobutyric acid, which is an amino acid derivative, and hydrochloric acid. It is commonly used in chemical research and is of interest in the field of medicinal chemistry. The compound has potential applications in the development of pharmaceuticals and agrochemicals due to its unique structure and properties. Its use may involve the synthesis of novel compounds for the treatment of various diseases or as a building block in the creation of new chemical entities. Overall, "R-3,4-Diaminobutyric acid 2HCl" has diverse potential applications in the chemical and pharmaceutical industries.

InChI:InChI=1/C4H10N2O2.2ClH/c5-2-3(6)1-4(7)8;;/h3H,1-2,5-6H2,(H,7,8);2*1H/t3-;;/m1../s1

Upstream product

• 141291-28-3 (4S)-4-(carbo-t-butoxymethyl)-imidazolidin-2-one 
• 141291-26-1 (4R)-4-(carbomethoxymethyl)-imidazolidin-2-one 

Relevant articles and documents

Synthesis of (R) and (S)-aminocarnitine, (R) and (S)-4-phosphonium-3-amino-butanoate, (R) and (S) 3,4-diaminobutanoic acid, and their derivatives starting from D- and L-aspartic acid

R or S aminocarnitine, R or S phosphonium aminocarnitine and R and S 3,4 diaminobutanoic acid, and their derivatives are prepared using starting from aspartic acid with the same configuration as the desired compounds. This process is advantageous from the industrial point of view in terms of the type of reactants used, the reduced volumes of solvents and the possibility of avoiding purification of the intermediate products.

Synthesis of (R) and (S)-aminocarnitine, (R) and (S)-4-phosphonium-3-amino-butanoate, (R) and (S) 3,4-diaminobutanoic acid, and their derivatives starting from D- and L-aspartic acid

A process is described for the preparation of R or S aminocarnitine, R or S phosphonium aminocarnitine and R and S 3,4 diaminobutanoic acid, and their derivatives with the following formula: where Y is as described in the attached description, starting from aspartic acid with the same configuration as the desired compounds. This process is advantageous from the industrial point of view in terms of the type of reactants used, the reduced volumes of solvents and the possibility of avoiding purification of the intermediate products.

Synthesis of (R)-3,4-diaminobutanoic acid by desymmetrization of dimethyl 3-(benzylamino)glutarate through enzymatic ammonolysis

Lipase B from Candida antarctica is shown to be a highly efficient catalyst for the desymmetrization of dimethyl 3-(benzylamino)glutarate (1) through aminolysis and ammonolysis reactions. Using this procedure, enantiopure monoamides are obtained in high yield. The synthetic value of these compounds is demonstrated by the preparation of an enantiopure nonnatural amino acid, i.e. (R)-3,4-diaminobutanoic acid [(+)-12].