1413431-89-6

Basic information

• Product Name: 2-(3-benzyl-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)propionic acid ethyl ester
• Synonyms: 2-(3-benzyl-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)propionic acid ethyl ester
• CAS NO: 1413431-89-6
• Molecular Weight: 318.373
• Mol File: 1413431-89-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3-benzyl-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)propionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-benzyl-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)propionic acid ethyl ester(1413431-89-6)
• EPA Substance Registry System: 2-(3-benzyl-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)propionic acid ethyl ester(1413431-89-6)

Safety Data

• Hazardous Substances Data: 1413431-89-6(Hazardous Substances Data)

Upstream product

• 77-71-4 5,5-dimethyl-imidazolidine-2,4-dione 
• 127834-98-4 2-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)propionic acid ethyl ester 
• 100-39-0 benzyl bromide 
• 535-11-5 Ethyl 2-bromopropionate 
• 1413431-92-1 (3-benzyl-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl pivalate 

Downstream Products

• 1413431-95-4 2-(3-benzyl-4,4-dimethyl-2-oxo-5-thioxoimidazolidin-1-yl)propionic acid ethyl ester 

Relevant articles and documents

Regioselective synthesis of 7,8-dihydroimidazo [5,1-c][1,2,4]triazine-3, 6(2H,4H)-dione derivatives: A new drug-like heterocyclic scaffold

Dihydroimidazo[5,1-c][1,2,4]triazine-3,6(2H,4H)-dione derivatives were prepared by successive N3- and N1-alkylation of hydantoins, followed by regioselective thionation and subsequent cyclization under mild conditions. In a final alkylation step a further substituent may be introduced. The synthetic strategy allows broad structural variation of this new drug-like heterobicyclic scaffold. In addition to extensive NMR and MS analyses, the structure of one derivative was confirmed by X-ray crystallography.