1413431-91-0

Basic information

• Product Name: 2-(4,4-dimethyl-2,5-dioxo-3-phenethylimidazolidin-1-yl)propionic acid ethyl ester
• CAS NO: 1413431-91-0
• Molecular Weight: 332.4
• Mol File: 1413431-91-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4,4-dimethyl-2,5-dioxo-3-phenethylimidazolidin-1-yl)propionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4,4-dimethyl-2,5-dioxo-3-phenethylimidazolidin-1-yl)propionic acid ethyl ester(1413431-91-0)
• EPA Substance Registry System: 2-(4,4-dimethyl-2,5-dioxo-3-phenethylimidazolidin-1-yl)propionic acid ethyl ester(1413431-91-0)

Safety Data

• Hazardous Substances Data: 1413431-91-0(Hazardous Substances Data)

Upstream product

• 535-11-5 Ethyl 2-bromopropionate 
• 127834-98-4 2-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)propionic acid ethyl ester 
• 103-63-9 1-phenyl-2-bromoethane 
• 77-71-4 5,5-dimethyl-imidazolidine-2,4-dione 

Relevant articles and documents

Regioselective synthesis of 7,8-dihydroimidazo [5,1-c][1,2,4]triazine-3, 6(2H,4H)-dione derivatives: A new drug-like heterocyclic scaffold

Dihydroimidazo[5,1-c][1,2,4]triazine-3,6(2H,4H)-dione derivatives were prepared by successive N3- and N1-alkylation of hydantoins, followed by regioselective thionation and subsequent cyclization under mild conditions. In a final alkylation step a further substituent may be introduced. The synthetic strategy allows broad structural variation of this new drug-like heterobicyclic scaffold. In addition to extensive NMR and MS analyses, the structure of one derivative was confirmed by X-ray crystallography.