141395-84-8Relevant articles and documents
PYRROLO-NITROGENOUS HETEROCYCLIC DERIVATIVES, THE PREPARATION AND THE PHARMACEUTICAL USE THEREOF
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Page/Page column 102-103, (2010/04/23)
The invention provides new pyrrolo-nitrogenous heterocyclic derivatives represented by formula (I) or their salts, the preparation thereof, pharmaceutical compositions containing such derivatives and the use of such derivatives as therapeutic agents, espe
Synthesis of the hypotensive agent 8-amino-7-[2-hydroxy-3-morpholinopropyl] theophylline (P23) and analogs
Cegla, Marek T.,Potaczek, Joanna,Zylewski, Marek,Strekowski, Lucjan
experimental part, p. 191 - 194 (2009/07/19)
Synthesis of a number of 7, 8-disubstituted theophyllines including enantiomers of the hypotensive agent P23 is described.
The synthesis of potent marcocyclic renin inhibitors
Dhanoa, Daljit S.,Parsons, William H.,Greenlee, William J.,Patchett, Arthur A.
, p. 1725 - 1728 (2007/10/02)
An efficient synthesis of a novel class of potent macrocylic renin inhibitors exemplified by compounds 1 and 2, which involves the marcocyclization of 8 and 9 as the key step, is described. The macrocyclic design of renin inhibitors 1 and 2 disclosed here