14143-01-2

Basic information

• Product Name: diethyl 3-methylphenyl phosphate
• Synonyms: Diethyl 3-methylphenyl phosphate; Phosphoric acid, diethyl 3-methylphenyl ester
• CAS NO: 14143-01-2
• Molecular Formula: C₁₁H₁₇O₄P
• Molecular Weight: 244.224
• Mol File: 14143-01-2.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 288.2°C at 760 mmHg
• Flash Point: 142°C
• Density: 1.13g/cm³
• Vapor Pressure: 0.00412mmHg at 25°C
• Refractive Index: 1.485
• CAS DataBase Reference: diethyl 3-methylphenyl phosphate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 3-methylphenyl phosphate(14143-01-2)
• EPA Substance Registry System: diethyl 3-methylphenyl phosphate(14143-01-2)

Safety Data

• Hazardous Substances Data: 14143-01-2(Hazardous Substances Data)

Upstream product

• 814-49-3 diethyl chlorophosphate 
• 108-39-4 3-methyl-phenol 
• 762-04-9 phosphonic acid diethyl ester 
• 32578-31-7 3-tolyl triflate 
• 54058-00-3 diethyl phosphite potassium salt 
• 125320-80-1 Dicyclohexyl-amine; compound with 3-methyl-phenol 
• 78-40-0 triethyl phosphate 

Downstream Products

• 80615-39-0 (2-Hydroxy-4-methyl-phenyl)-phosphonic acid diethyl ester 
• 129529-19-7 2-(Diethyl-phosphinoyl)-5-methyl-phenol 
• 17171-17-4 4'-methoxy-3-methylbiphenyl 
• 7025-91-4 4-m-tolylmorpholine 
• 253342-48-2 4,4,5,5-tetramethyl-2-m-tolyl-1,3,2-dioxaborolane 

Relevant articles and documents

Electrochemical phosphorylation of arenols and anilines leading to organophosphates and phosphoramidates

A practical phosphorylation for generating organophosphates and phosphoramidatesviaelectrochemical dehydrogenative cross-coupling of P(O)H compounds with arenols and anilines is disclosed. This method involves using inorganic iodide salts as both redox catalysts and electrolytes in an undivided cell without the addition of oxidants or bases. A preliminary mechanistic study suggests that radicals are not involved in this process. This method is green and eco-friendly and has good functional group tolerance, high yields and broad substrate scope, with the potential for practical synthesis.

Enantioselective and Regioselective Hydroetherification of Alkynes by Gold-Catalyzed Desymmetrization of Prochiral Phenols with P-Stereogenic Centers

The gold(I)-catalyzed enantioselective hydroetherification of alkynes was achieved via desymmetrization of prochiral bisphenols bearing P-stereogenic centers. (S)-DTBM-Segphos(AuCl)2/AgNTf2 proved to be a highly efficient catalyst system for this transformation, affording P-chiral cyclic phosphine oxides in good yields with high enantioselectivities (with up to 99% ee). The same catalyst system allowed for the enantioselective desymmetrization of dialkynes. Synthetic transformations of the cyclization products afforded other P-chiral molecules with high enantiospecificity.

Pd(II)-catalyzed ortho-arylation of aryl phosphates and aryl hydrogen phosphates with diaryliodonium triflates

Functionalized biaryl compounds were successfully synthesized using phosphates as the ortho-directing group in the Pd(II)/Pd(IV) catalytic cycle.