141437-91-4Relevant articles and documents
"Mixed Inhibitor-Prodrug" as a New Approach toward Systemically Active Inhibitors of Enkephalin-Degrading Enzymes
Fournie-Zaluski, Marie-Claude,Coric, Pascal,Turcaud, Serge,Lucas, Evelyne,Noble, Florence,et al.
, p. 2473 - 2481 (2007/10/02)
In order to evaluate the possible advantages of potentiating the effects of the endogenous enkephalins, to obtain analgesia without the serious drawbacks of morphine, it was essential to design systemically active compounds which inhibit the two metaboliz