141459-28-1

Basic information

• Product Name: (CYS3,6,TYR8,PRO9)-SUBSTANCE P
• Synonyms: (CYS3,6,TYR8,PRO9)-SUBSTANCE P;H-ARG-PRO-CYS-PRO-GLN-CYS-PHE-TYR-PRO-LEU-MET-NH2;H-ARG-PRO-CYS-PRO-GLN-CYS-PHE-TYR-PRO-LEU-MET-NH2 (DISULFIDE BRIDGE: 3-6);RPCPQCFYPLM-NH2 (DISULFIDE BRIDGE: 3-6);H-Arg-Pro-Cys-Pro-Gln-Cys-Phe-Tyr-Pro-Leu-Met-NH2 (Disulfide bond)
• CAS NO: 141459-28-1
• Molecular Formula: C61H90N16O13S3
• Molecular Weight: 1351.66
• Product Categories: peptide
• Mol File: 141459-28-1.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.50±0.1 g/cm3(Predicted)
• PKA: 9.83±0.15(Predicted)
• CAS DataBase Reference: (CYS3,6,TYR8,PRO9)-SUBSTANCE P(CAS DataBase Reference)
• NIST Chemistry Reference: (CYS3,6,TYR8,PRO9)-SUBSTANCE P(141459-28-1)
• EPA Substance Registry System: (CYS3,6,TYR8,PRO9)-SUBSTANCE P(141459-28-1)

Safety Data

• Hazardous Substances Data: 141459-28-1(Hazardous Substances Data)

Usage

Description

(CYS3,6,TYR8,PRO9)-SUBSTANCE P is a neuropeptide composed of 11 amino acids that functions as a neurotransmitter and neuromodulator in the central and peripheral nervous systems. It is crucial in pain sensation, inflammation, mood regulation, and neurogenic inflammation. The peptide is released from sensory nerve endings and interacts with its receptors, NK1, NK2, and NK3, to transmit pain signals and mediate the inflammatory response.

Uses

Used in Pharmaceutical Industry:
(CYS3,6,TYR8,PRO9)-SUBSTANCE P is used as a target for drug development for various applications, including pain management, arthritis, and neurodegenerative diseases. Its involvement in physiological and pathological processes makes it a promising candidate for the creation of new therapeutic agents.
Used in Pain Management:
(CYS3,6,TYR8,PRO9)-SUBSTANCE P is used as a target for the development of pain-relieving drugs. By modulating the activity of this neuropeptide, researchers aim to alleviate pain sensations and provide relief to patients suffering from various types of pain.
Used in Arthritis Treatment:
(CYS3,6,TYR8,PRO9)-SUBSTANCE P is used as a target for the development of treatments for arthritis. Since it plays a role in inflammation, modulating its activity can potentially help reduce the inflammation associated with arthritis and improve the quality of life for patients.
Used in Neurodegenerative Disease Research:
(CYS3,6,TYR8,PRO9)-SUBSTANCE P is used as a target for research into neurodegenerative diseases. Understanding the role of this neuropeptide in mood regulation and neurogenic inflammation can lead to the development of new treatments for conditions such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis.