141478-73-1

Basic information

• Product Name: 2-Cyclohexen-1-one, 5-ethyl-4-hydroxy-4-(phenylethynyl)-, trans-
• CAS NO: 141478-73-1
• Molecular Formula: C16H16O2
• Molecular Weight: 240.302
• Mol File: 141478-73-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Cyclohexen-1-one, 5-ethyl-4-hydroxy-4-(phenylethynyl)-, trans-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexen-1-one, 5-ethyl-4-hydroxy-4-(phenylethynyl)-, trans-(141478-73-1)
• EPA Substance Registry System: 2-Cyclohexen-1-one, 5-ethyl-4-hydroxy-4-(phenylethynyl)-, trans-(141478-73-1)

Safety Data

• Hazardous Substances Data: 141478-73-1(Hazardous Substances Data)

Upstream product

• 2386-64-3 ethylmagnesium chloride 
• 106-51-4 p-benzoquinone 
• 4440-01-1 lithium phenylacetylide 

Downstream Products

• 141478-81-1 C₁₈H₂₀O₂ 
• 141478-81-1 (3R,4R,5S)-3-Ethyl-4-hydroxy-4-phenylethynyl-5-vinyl-cyclohexanone 

Relevant articles and documents

Complementary facial selectivity in conjugate additions to γ-hydroxyenones

Complementary facial selectivity can be achieved in conjugate additions to γ-hydroxyenones by using either Grignard reagents or cuprates. In the case of the former, preliminary complexation of the magnesium reagent with the resident alkoxide, followed by alkyl group transfer, results in the exclusive formation of the syn product. Conversely, cuprate conjugate additions proceed in an anti fashion, presumably because, in this mode of addition, coulombic repulsions are minimized.