14148-42-6

Basic information

• Product Name: 8-hydrazinylquinoline hydrochloride
• Synonyms: 8-hydrazinylquinoline hydrochloride
• CAS NO: 14148-42-6
• Molecular Formula: C₉H₉N₃
• Molecular Weight: 195.6488
• Mol File: 14148-42-6.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-hydrazinylquinoline hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 8-hydrazinylquinoline hydrochloride(14148-42-6)
• EPA Substance Registry System: 8-hydrazinylquinoline hydrochloride(14148-42-6)

Safety Data

• Hazardous Substances Data: 14148-42-6(Hazardous Substances Data)

Usage

General Description

8-hydrazinylquinoline hydrochloride is a chemical compound that belongs to the quinoline family and possesses a hydrazine functional group. It is commonly used in organic synthesis as a versatile building block for the preparation of various pharmaceutical compounds and organic materials. The hydrochloride salt form of 8-hydrazinylquinoline is often preferred for its increased stability and solubility in water. 8-hydrazinylquinoline hydrochloride is known for its potential as a chelating agent in metal-ion complexation and has been studied for its anti-tumor and anti-bacterial properties. Additionally, 8-hydrazinylquinoline hydrochloride has been investigated for its fluorescent properties and potential applications in bioimaging and sensor technologies. Overall, this chemical compound has versatile applications in various fields, including pharmaceuticals, materials science, and chemical research.

Upstream product

• 148-24-3 8-quinolinol 
• 578-66-5 8-amino quinoline 
• 16567-18-3 8-bromoquinoline 
• 5350-57-2 benzophenone hydrazone 
• 913839-70-0 2‐[2‐(diphenylmethylidene)hydrazin‐1‐yl]‐4‐methoxypyridine 

Downstream Products

• 86444-92-0 benzilic acid 8-quinolylhydrazide 
• 86444-93-1 Bis-(4-fluoro-phenyl)-hydroxy-acetic acid N'-quinolin-8-yl-hydrazide 
• 86444-94-2 Bis-(4-chloro-phenyl)-hydroxy-acetic acid N'-quinolin-8-yl-hydrazide 
• 88673-65-8 Hydroxy-di-p-tolyl-acetic acid N'-quinolin-8-yl-hydrazide 
• 88673-64-7 Hydroxy-di-m-tolyl-acetic acid N'-quinolin-8-yl-hydrazide 
• 88673-70-5 β-N-acetyl-8-quinolylhydrazide of benzilic acid 
• 88673-66-9 Hydroxy-bis-(4-methoxy-phenyl)-acetic acid N'-quinolin-8-yl-hydrazide 
• 88673-67-0 Hydroxy-bis-(2-methoxy-phenyl)-acetic acid N'-quinolin-8-yl-hydrazide 
• 88673-72-7 Acetic acid N'-[2-hydroxy-2,2-bis-(4-methoxy-phenyl)-acetyl]-N-quinolin-8-yl-hydrazide 
• 88673-75-0 N-acetyl-8-(β-benziloylhydrazino)quinolinium chloride 
• 86445-00-3 3-Phenyl-1-(quinolin-8-ylamino)-1,3-dihydro-indol-2-one 
• 1248801-79-7 2,2-bis(diphenylphosphino)-1-(quinolyl-8)-hydrazine 
• 908129-34-0 (S)-2-(1,3-dioxoisoindolin-2-yl)-3-phenyl-N-(quinolin-8-yl)propanamide 

Relevant articles and documents

Design of receptors for urea derivatives based on the pyrido[3,2-g]indole subunit

The Fischer cyclization of appropriate 8-quinolinylhydrazones was employed to prepare a series of cavity-shaped hosts consisting of a central pyridine ring appended in either the 2,6- or 3,5-positions by two pyrido[3,2-g]indole subunits. The pyridine and

PHOTOCHROMIC HYDRAZONE SWITCHES

Provided herein are compounds for use as photochromic molecular switches having very long thermal isomerization half-lives and switchable fluorescence properties both in solution and the solid state.

Catalytic Coupling between Unactivated Aliphatic C-H Bonds and Alkynes via a Metal-Hydride Pathway

We report a Rh(I)-catalyzed site-selective coupling between ketone β-C(sp3)-H bonds and aliphatic alkynes using an in situ-installed directing group. Upon hydrogenation or hydration, various β-alkylation or β-aldol products of the ketones are obtained with broad functional group tolerance. Mechanistic investigations support the involvement of a Rh-H intermediate through oxidative addition of Rh(I) into the β-C-H bonds. Thus, to the best of our knowledge, this transformation represents the first example of catalytic couplings between unsaturated hydrocarbons and unactivated aliphatic C-H bonds via a metal-hydride pathway.